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> Protein (NX_Q9UHP6)
Protein (NX_Q9UHP6)
Protein
Gene SymbolRTDR1 to neXtProt (NX_Q9UHP6)
DescriptionRhabdoid tumor deletion region protein 1
Chromosome22
Location22q11.22 (23401593 ~ 23487208) to Ensembl
Sequene Features : Isoforms 1, Variants 55, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 55 0
2014-09-19protein level
1 45 0
2014-05-27protein level
1 45 0
2014-02-25protein level
1 45 0
2013-12-09protein level
1 37 0
2013-11-01protein level
1 34 0
2013-09-12protein level
1 34 0
2013-08-17protein level
1 34 0
2013-07-15protein level
1 26 0
2013-06-11protein level
1 26 0
2013-02-12protein level
1 18 0
2012-12-20protein level
1 18 0
2012-10-30protein level
1 18 0
2012-10-07protein level
1 18 0
2012-08-24transcript level
1 14 0
2012-07-28transcript level
1 14 0
2012-06-08transcript level
1 15 0
2012-05-07transcript level
1 14 0
2012-04-10transcript level
1 14 0
2012-01-13transcript level
1 6 0
2011-12-20transcript level
1 6 0
2011-11-11transcript level
1 6 0
2011-08-23transcript level
1 6 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9UHP6-1
19 0 0 38567.3028
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-748350,EBI-533224 TCF4  
  .protein-DNA complex assembly
.positive regulation of transcription from RNA polymerase II promoter
.positive regulation of transcription, DNA-templated
  + 3 more...
.E-box binding
.protein heterodimerization activity
.bHLH transcription factor binding
  + 9 more...
.transcription factor complex
.nucleus
2 EBI-748350,EBI-1181367 CDR2  
  .N/A .N/A .cytoplasm
3 EBI-748350,EBI-307352 REL  
  .negative regulation of neuron death
.positive regulation of transcription from RNA polymerase II promoter
.innate immune response
  + 10 more...
.sequence-specific DNA binding transcription factor activity
.chromatin binding
.RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.RNA polymerase II distal enhancer sequence-specific DNA binding
.I-kappaB/NF-kappaB complex
.cytosol
.transcription factor complex
  + 2 more...
4 EBI-748350,EBI-618165 GABPB1  
  .positive regulation of transcription from RNA polymerase II promoter
.mitochondrion organization
.organelle organization
  + 2 more...
.protein heterodimerization activity
.transcription regulatory region DNA binding
.sequence-specific DNA binding transcription factor activity
.nucleoplasm
.nucleus
5 EBI-748350,EBI-618309 GOLGA2  
  .negative regulation of protein binding
.mitotic cell cycle
.syntaxin binding
.protein kinase binding
.Golgi cisterna membrane
.ER to Golgi transport vesicle
.cis-Golgi network
  + 4 more...
6 EBI-748350,EBI-948001 KRT31  
  .epidermis development .structural constituent of cytoskeleton .extracellular exosome
.intermediate filament
.extracellular space
7 EBI-748350,EBI-10171697 KRT40  
  .N/A .structural molecule activity .intermediate filament
8 EBI-748350,EBI-749955 TRIM69  
  .apoptotic process .ligase activity
.zinc ion binding
.ubiquitin-protein transferase activity
.nuclear speck
.plasma membrane
.cytoplasm
.nucleus
9 EBI-748350,EBI-2125614 KIFC3  
  .epithelial cell-cell adhesion
.zonula adherens maintenance
.metabolic process
  + 3 more...
.ATPase activity
.ATP binding
.microtubule motor activity
.extracellular exosome
.cytoplasmic vesicle membrane
.zonula adherens
  + 4 more...
10 EBI-748350,EBI-2371151 AP3M1  
  .anterograde synaptic vesicle transport
.anterograde axon cargo transport
.protein targeting to lysosome
.Rab GTPase binding .cytoplasmic vesicle membrane
.clathrin adaptor complex
.Golgi apparatus
  + 2 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
brain3
connective tissue6
eye4
intestine4
kidney9
lung20
lymph22
pharynx24
stomach10
testis22
uterus4
Health State
TissuesTPM*
normal11
adrenal tumor79
chondrosarcoma12
gastrointestinal tumor8
germ cell tumor3
lymphoma13
uterine tumor11
Developmental Stage
TissuesTPM*
adult3
fetus17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adrenal gland2.1
cerebral cortex1.3
kidney5.6
lung1.4
ovary2.4
skin1.1
testis15.5
thyroid gland1
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*605663, gene) Rhabdoid tumor deletion region gene 1; RTDR1OMIM


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