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> Protein (NX_Q9UI08)
Protein (NX_Q9UI08)
Protein
Gene SymbolEVL to neXtProt (NX_Q9UI08)
DescriptionEna/VASP-like protein
Chromosome14
Location14q32.2 (100437786 ~ 100610573) to Ensembl
Sequene Features : Isoforms 3, Variants 48, PTMs 10 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of ruffle assembly
.positive regulation of stress fiber assembly
.protein homotetramerization
  + 9 more...
.SH3 domain binding
.profilin binding
.lamellipodium
.membrane
.focal adhesion
  + 3 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 48 10
2014-09-19protein level
2 36 10
2014-05-27protein level
2 36 10
2014-02-25protein level
2 36 10
2013-12-09protein level
2 31 10
2013-11-01protein level
2 25 10
2013-09-12protein level
2 25 11
2013-08-17protein level
2 25 11
2013-07-15protein level
2 15 10
2013-06-11protein level
2 15 10
2013-02-12protein level
2 7 22
2012-12-20protein level
2 7 22
2012-10-30protein level
2 8 22
2012-10-07protein level
2 8 11
2012-08-24protein level
2 8 11
2012-07-28protein level
2 8 11
2012-06-08protein level
2 11 11
2012-05-07protein level
2 10 11
2012-04-10protein level
2 10 11
2012-01-13protein level
2 7 11
2011-12-20protein level
2 7 11
2011-11-11protein level
2 7 11
2011-08-23protein level
2 7 11
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9UI08-1
0 21 1 44592.089
NX_Q9UI08-2
1 21 0 44764.1733
NX_Q9UI08-3
2 17 0 41551.5167
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-6448852,EBI-466029 HTT  
  .negative regulation of extrinsic apoptotic signaling pathway
.iron ion homeostasis
.L-glutamate import
  + 38 more...
.diazepam binding
.beta-tubulin binding
.dynein intermediate chain binding
  + 6 more...
.protein complex
.cytoplasmic vesicle membrane
.dendrite
  + 11 more...
2 EBI-346653,EBI-351450 SPTAN1  
  .actin filament capping
.programmed cell death
.axon guidance
  + 2 more...
.calcium ion binding
.structural constituent of cytoskeleton
.actin binding
.extracellular exosome
.intracellular membrane-bounded organelle
.cuticular plate
  + 8 more...
3 EBI-6448852,EBI-524753 ZDHHC17  
  .positive regulation of I-kappaB kinase/NF-kappaB signaling
.lipoprotein transport
.protein palmitoylation
  + 2 more...
.identical protein binding
.protein-cysteine S-palmitoyltransferase activity
.palmitoyltransferase activity
  + 3 more...
.intracellular membrane-bounded organelle
.Golgi-associated vesicle membrane
.integral component of membrane
  + 3 more...
4 EBI-346653,EBI-720828 TRIM9  
  .negative regulation of calcium ion-dependent exocytosis
.proteasome-mediated ubiquitin-dependent protein catabolic process
.negative regulation of SNARE complex assembly
.synaptic vesicle exocytosis
.protein homodimerization activity
.ligase activity
.zinc ion binding
.ubiquitin-protein transferase activity
.dendrite
.cell junction
.synaptic vesicle
  + 2 more...
5 EBI-346653,EBI-742038 ABI3  
  .regulation of cell migration
.movement of cell or subcellular component
.N/A .lamellipodium
.membrane
.cytoplasm
.intracellular
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites25
bladder33
blood147
bone55
bone marrow20
brain178
cervix61
connective tissue53
embryonic tissue61
eye244
heart189
intestine38
kidney66
larynx127
liver38
lung140
lymph135
lymph node211
mammary gland152
muscle37
nerve64
pancreas149
pharynx49
pituitary gland60
placenta74
prostate73
salivary gland98
skin28
spleen318
stomach31
testis45
thymus727
thyroid42
tonsil705
trachea19
uterus103
vascular116
Health State
TissuesTPM*
normal143
bladder carcinoma56
breast (mammary gland) tumor182
cervical tumor57
chondrosarcoma72
colorectal tumor8
gastrointestinal tumor33
germ cell tumor45
glioma167
head and neck tumor37
kidney tumor130
leukemia158
liver tumor31
lung tumor214
lymphoma304
non-neoplasia103
pancreatic tumor123
primitive neuroectodermal tumor of the CNS94
prostate cancer67
retinoblastoma236
skin tumor7
soft tissue/muscle tissue tumor39
uterine tumor144
Developmental Stage
TissuesTPM*
adult134
embryoid body57
blastocyst65
neonate32
fetus204
infant42
juvenile305
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue36.9
adrenal gland38.3
appendix156.2
bone marrow48.4
cerebral cortex118.9
colon28.3
duodenum43.5
esophagus32.3
gallbladder65.5
heart muscle44.4
kidney22.4
liver24.8
lung81.2
lymph node233.9
ovary58.1
pancreas20.7
placenta37.7
prostate48.5
salivary gland43.6
skin62
small intestine64.9
spleen168.9
stomach52.3
testis48.8
thyroid gland27.7
urinary bladder55.5
Tissues
TissuesExpression level
appendixHigh
bone marrowHigh
breastMedium
cerebellumLow
cerebral cortexMedium
colonLow
hippocampusLow
lateral ventricleLow
lungHigh
lymph nodeHigh
soft tissue 2Low
spleenHigh
tonsilHigh
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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