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> Protein (NX_Q9UI14)
Protein (NX_Q9UI14)
Protein
Gene SymbolRABAC1 to neXtProt (NX_Q9UI14)
DescriptionPrenylated Rab acceptor protein 1
Chromosome19
Location19q13.2 (42460833 ~ 42463542) to Ensembl
Sequene Features : Isoforms 1, Variants 19, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .identical protein binding .cell junction
.integral component of membrane
.membrane
  + 3 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 19 3
2014-09-19protein level
1 13 3
2014-05-27protein level
1 13 3
2014-02-25protein level
1 13 3
2013-12-09protein level
1 10 3
2013-11-01protein level
1 10 2
2013-09-12protein level
1 10 2
2013-08-17protein level
1 10 2
2013-07-15protein level
1 9 2
2013-06-11protein level
1 9 2
2013-02-12protein level
1 6 2
2012-12-20protein level
1 7 2
2012-10-30protein level
1 6 2
2012-10-07protein level
1 6 2
2012-08-24protein level
1 6 2
2012-07-28protein level
1 6 2
2012-06-08protein level
1 9 2
2012-05-07protein level
1 9 2
2012-04-10protein level
1 9 2
2012-01-13protein level
1 9 2
2011-12-20protein level
1 9 2
2011-11-11protein level
1 9 2
2011-08-23protein level
1 9 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9UI14-1
6 0 0 20634.6902
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-712367,EBI-985879 SNCA  
  .regulation of reactive oxygen species biosynthetic process
.regulation of synaptic vesicle recycling
.positive regulation of hydrogen peroxide catabolic process
  + 63 more...
.phosphoprotein binding
.tau protein binding
.dynein binding
  + 14 more...
.perinuclear region of cytoplasm
.fibril
.terminal bouton
  + 21 more...
2 EBI-712367,EBI-740459 FXR2  
  .negative regulation of translation
.positive regulation of defense response to virus by host
.poly(A) RNA binding
.identical protein binding
.mRNA binding
.RNA binding
.extracellular exosome
.cytosolic large ribosomal subunit
.membrane
  + 3 more...
3 EBI-712367,EBI-742790 TRIM32  
  .positive regulation of cell motility
.negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
.negative regulation of viral release from host cell
  + 21 more...
.ubiquitin protein ligase activity
.protein self-association
.ubiquitin binding
  + 8 more...
.striated muscle myosin thick filament
.cytosol
.cytoplasm
.nucleus
4 EBI-712367,EBI-2822329 SNX1  
  .lamellipodium morphogenesis
.positive regulation of protein catabolic process
.retrograde transport, endosome to Golgi
  + 4 more...
.leptin receptor binding
.transferrin receptor binding
.identical protein binding
  + 3 more...
.protein complex
.intracellular membrane-bounded organelle
.early endosome membrane
  + 8 more...
5 EBI-712367,EBI-744685 RAB33A  
  .regulation of autophagic vacuole assembly
.Rab protein signal transduction
.antigen processing and presentation
  + 2 more...
.GTP binding
.GTPase activity
.plasma membrane
.Golgi apparatus
6 EBI-712367,EBI-10238936 SYT16  
  .synaptic vesicle exocytosis
.vesicle fusion
.clathrin binding
.syntaxin binding
.phospholipid binding
.calcium ion binding
.plasma membrane
7 EBI-712367,EBI-740486 NUDT18  
  .nucleobase-containing small molecule metabolic process
.GDP catabolic process
.dGDP catabolic process
  + 3 more...
.8-hydroxy-dADP phosphatase activity
.8-oxo-GDP phosphatase activity
.8-oxo-dGDP phosphatase activity
.magnesium ion binding
.cytosol
8 EBI-712367,EBI-745535 ADCK3  
  .phosphorylation
.ubiquinone biosynthetic process
.ADP binding
.kinase activity
.ATP binding
.integral component of membrane
.mitochondrion
9 EBI-712367,EBI-750153 MIEF2  
  .positive regulation of protein targeting to membrane
.positive regulation of mitochondrial fission
.positive regulation of protein homooligomerization
.mitochondrion organization
.N/A .integral component of membrane
.mitochondrial outer membrane
.mitochondrion
10 EBI-712367,EBI-741158 WDYHV1  
  .cellular protein modification process .protein-N-terminal glutamine amidohydrolase activity .cytosol
.nucleus
11 EBI-712367,EBI-2849569 ZFYVE21  
  .N/A .metal ion binding .cytoplasmic membrane-bounded vesicle
.focal adhesion
.endosome
12 EBI-712367,EBI-740897 NIF3L1  
  .negative regulation of nucleic acid-templated transcription
.positive regulation of transcription, DNA-templated
.neuron differentiation
.identical protein binding
.transcription factor binding
.mitochondrion
.cytoplasm
.nucleus
13 EBI-712367,EBI-742388 PLEKHF2  
  .protein transport .metal ion binding .early endosome membrane
.transport vesicle
.endoplasmic reticulum
14 EBI-712367,EBI-9091816 RIC8A  
  .basement membrane organization
.cell-cell adhesion involved in gastrulation
.positive regulation of GTPase activity
  + 6 more...
.GTPase activator activity
.guanyl-nucleotide exchange factor activity
.G-protein alpha-subunit binding
.plasma membrane
.cytoplasm
15 EBI-712367,EBI-725924 SNX15  
  .intracellular protein transport .phosphatidylinositol binding .cytoplasmic vesicle membrane
.membrane
.cytosol
  + 2 more...
16 EBI-712367,EBI-742688 SPG21  
  .antigen receptor-mediated signaling pathway .CD4 receptor binding .trans-Golgi network transport vesicle
.endosome membrane
.cytosol
  + 3 more...
17 EBI-712367,EBI-10323810 NDRG4  
  .positive regulation of ERK1 and ERK2 cascade
.cardiac muscle cell proliferation
.negative regulation of smooth muscle cell proliferation
  + 9 more...
.N/A .basolateral plasma membrane
.cytosol
.endoplasmic reticulum membrane
  + 2 more...
18 EBI-712367,EBI-8084503 NDRG2  
  .regulation of platelet-derived growth factor production
.negative regulation of ERK1 and ERK2 cascade
.negative regulation of smooth muscle cell proliferation
  + 6 more...
.N/A .extracellular exosome
.perinuclear region of cytoplasm
.growth cone
  + 6 more...
19 EBI-712367,EBI-715161 DUSP12  
  .peptidyl-tyrosine dephosphorylation
.positive regulation of glucokinase activity
.protein dephosphorylation
.cellular protein modification process
.zinc ion binding
.protein tyrosine/serine/threonine phosphatase activity
.protein tyrosine phosphatase activity
.cytoplasm
.nucleus
20 EBI-712367,EBI-719396 WIPI2  
  .nucleophagy
.protein localization to pre-autophagosomal structure
.cellular response to nitrogen starvation
  + 3 more...
.phosphatidylinositol-3,5-bisphosphate binding
.phosphatidylinositol-3-phosphate binding
.protein complex
.pre-autophagosomal structure membrane
.extrinsic component of membrane
  + 4 more...
21 EBI-712367,EBI-10329449 SNX11  
  .vesicle organization
.endocytosis
.intracellular protein transport
.phosphatidylinositol phosphate binding .extrinsic component of membrane
.endosome
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland60
ascites25
blood16
bone111
brain51
connective tissue80
embryonic tissue65
esophagus99
eye57
heart22
intestine43
kidney23
liver9
lung71
lymph225
lymph node66
mammary gland33
mouth45
ovary88
pancreas609
pharynx24
pituitary gland121
placenta52
prostate63
salivary gland98
skin113
stomach73
testis22
tonsil58
uterus17
vascular19
Health State
TissuesTPM*
normal40
adrenal tumor79
breast (mammary gland) tumor53
chondrosarcoma193
colorectal tumor8
esophageal tumor115
gastrointestinal tumor50
germ cell tumor49
glioma83
head and neck tumor44
kidney tumor43
leukemia10
lung tumor97
lymphoma138
non-neoplasia51
ovarian tumor65
pancreatic tumor1238
primitive neuroectodermal tumor of the CNS78
prostate cancer96
skin tumor87
soft tissue/muscle tissue tumor31
Developmental Stage
TissuesTPM*
adult59
embryoid body71
blastocyst81
fetus21
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue53.9
adrenal gland50.5
appendix47.7
bone marrow30.4
cerebral cortex51.2
colon63.1
duodenum58
esophagus27.9
gallbladder36.8
heart muscle30.9
kidney61.2
liver28.8
lung57.1
lymph node43.7
ovary44.5
pancreas53.4
placenta53.9
prostate55.7
salivary gland72.4
skin39.8
small intestine54.5
spleen50.3
stomach83.6
testis53.8
thyroid gland33.6
urinary bladder48.3
Tissues
TissuesExpression level
appendixMedium
bone marrowMedium
breastLow
bronchusMedium
cerebellumMedium
cerebral cortexMedium
cervix, uterineHigh
colonMedium
duodenumMedium
endometrium 1Medium
endometrium 2Medium
epididymisMedium
esophagusHigh
fallopian tubeMedium
gallbladderMedium
heart muscleMedium
hippocampusMedium
kidneyHigh
lateral ventricleLow
liverMedium
lungLow
lymph nodeMedium
nasopharynxMedium
oral mucosaHigh
ovaryMedium
pancreasHigh
parathyroid glandLow
placentaMedium
prostateMedium
rectumHigh
salivary glandMedium
seminal vesicleMedium
skeletal muscleMedium
skin 1Low
skin 2Medium
small intestineMedium
smooth muscleMedium
soft tissue 1Low
soft tissue 2Low
spleenLow
stomach 1Medium
stomach 2Medium
testisMedium
thyroid glandLow
tonsilMedium
urinary bladderLow
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*604925, gene) Rab acceptor 1; RABAC1OMIM


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2014-2019 (C) Yonsei Proteome Research Center