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> Protein (NX_Q9UI47)
Protein (NX_Q9UI47)
Protein
Gene SymbolCTNNA3 to neXtProt (NX_Q9UI47)
DescriptionCatenin alpha-3
Chromosome10
Location10q21.3 (67672276 ~ 69455927) to Ensembl
Sequene Features : Isoforms 2, Variants 222, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of ventricular cardiac muscle cell action potential
.regulation of heart rate by cardiac conduction
.bundle of His cell-Purkinje myocyte adhesion involved in cell communication
.single organismal cell-cell adhesion
.cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication
.cadherin binding
.beta-catenin binding
.lamellipodium
.fascia adherens
.cytoskeleton
.cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 222 2
2014-09-19protein level
2 171 2
2014-05-27protein level
2 169 2
2014-02-25protein level
2 169 2
2013-12-09protein level
2 145 2
2013-11-01protein level
2 133 2
2013-09-12protein level
2 133 2
2013-08-17protein level
2 133 2
2013-07-15protein level
2 92 2
2013-06-11protein level
2 92 2
2013-02-12protein level
2 33 2
2012-12-20protein level
2 31 2
2012-10-30protein level
2 44 2
2012-10-07protein level
2 44 2
2012-08-24protein level
2 32 2
2012-07-28protein level
2 32 2
2012-06-08protein level
2 3 2
2012-05-07protein level
2 3 2
2012-04-10protein level
2 3 2
2012-01-13protein level
2 3 2
2011-12-20protein level
2 3 2
2011-11-11protein level
2 3 2
2011-08-23protein level
2 3 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9UI47-1
21 20 1 99745.2835
NX_Q9UI47-2
1 20 0 57295.664
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
brain5
connective tissue207
embryonic tissue4
heart11
nerve64
testis2
trachea19
Health State
TissuesTPM*
normal2
non-neoplasia20
soft tissue/muscle tissue tumor247
Developmental Stage
TissuesTPM*
adult2
blastocyst16
fetus1
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
appendix1.5
cerebral cortex4.4
esophagus2.5
gallbladder1.3
heart muscle22.7
liver2.7
ovary1.7
testis12.6
urinary bladder1.6
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*607667, gene) Catenin, alpha-3; CTNNA3OMIM


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