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> Protein (NX_Q9UIF8)
Protein (NX_Q9UIF8)
Protein
Gene SymbolBAZ2B to neXtProt (NX_Q9UIF8)
DescriptionBromodomain adjacent to zinc finger domain protein 2B
Chromosome2
Location2q24.2 (160175490 ~ 160473203) to Ensembl
Sequene Features : Isoforms 5, Variants 282, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.zinc ion binding
.DNA binding
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
5 282 8
2014-09-19protein level
5 207 8
2014-05-27protein level
5 207 8
2014-02-25protein level
5 206 8
2013-12-09protein level
5 152 8
2013-11-01protein level
5 144 8
2013-09-12protein level
5 144 8
2013-08-17protein level
5 144 8
2013-07-15protein level
5 81 8
2013-06-11protein level
5 81 8
2013-02-12protein level
5 20 30
2012-12-20protein level
5 18 30
2012-10-30protein level
5 35 30
2012-10-07protein level
5 35 6
2012-08-24protein level
5 29 6
2012-07-28protein level
5 29 6
2012-06-08protein level
5 39 6
2012-05-07protein level
5 39 6
2012-04-10protein level
5 39 6
2012-01-13protein level
5 23 6
2011-12-20protein level
5 23 6
2011-11-11protein level
5 23 6
2011-08-23protein level
5 23 6
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9UIF8-1
0 86 0 240309.8458
NX_Q9UIF8-2
1 82 0 230011.3188
NX_Q9UIF8-3
0 83 0 236403.966
NX_Q9UIF8-4
0 81 0 220573.2395
NX_Q9UIF8-5
0 83 0 236275.9078
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10321972,EBI-10176632 ZBTB14  
  .negative regulation of transcription, DNA-templated
.transcription from RNA polymerase II promoter
.negative regulation of transcription from RNA polymerase II promoter
.metal ion binding
.transcription regulatory region DNA binding
.sequence-specific DNA binding
  + 2 more...
.cytoplasm
.nucleoplasm
.nucleus
2 EBI-10321972,EBI-740459 FXR2  
  .negative regulation of translation
.positive regulation of defense response to virus by host
.poly(A) RNA binding
.identical protein binding
.mRNA binding
.RNA binding
.extracellular exosome
.cytosolic large ribosomal subunit
.membrane
  + 3 more...
3 EBI-10321972,EBI-742740 ZBTB8A  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
4 EBI-10321972,EBI-745680 STAC3  
  .skeletal muscle fiber development
.intracellular signal transduction
.neuromuscular synaptic transmission
.skeletal muscle contraction
.metal ion binding
.identical protein binding
.N/A
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland60
ascites25
bladder66
blood40
bone41
bone marrow20
brain29
cervix20
connective tissue6
ear62
embryonic tissue61
eye81
heart22
intestine25
kidney28
liver38
lung20
lymph node11
mammary gland66
mouth120
muscle103
nerve64
ovary118
pancreas74
parathyroid48
pharynx98
pituitary gland181
placenta56
prostate52
skin14
spleen37
stomach20
testis48
thymus50
thyroid21
trachea57
uterus56
vascular38
Health State
TissuesTPM*
normal51
adrenal tumor79
breast (mammary gland) tumor42
chondrosarcoma24
colorectal tumor35
gastrointestinal tumor25
germ cell tumor34
glioma46
head and neck tumor67
kidney tumor43
leukemia42
liver tumor10
non-neoplasia41
ovarian tumor118
prostate cancer38
skin tumor23
soft tissue/muscle tissue tumor23
uterine tumor55
Developmental Stage
TissuesTPM*
adult57
embryoid body85
blastocyst32
neonate32
fetus48
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue18.4
adrenal gland25.2
appendix18.7
bone marrow22.7
cerebral cortex22
colon17.9
duodenum14.2
esophagus22.2
gallbladder29.4
heart muscle14.6
kidney17.2
liver10.9
lung22.8
lymph node15.6
ovary40.2
pancreas8.4
placenta19.2
prostate16.7
salivary gland15.6
skin15.5
small intestine15.3
spleen19.7
stomach15
testis33.1
thyroid gland25.2
urinary bladder24.8
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*605683, gene) Bromodomain adjacent to zinc finger domain, 2b; BAZ2BOMIM


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