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> Protein (NX_Q9UII6)
Protein (NX_Q9UII6)
Protein
Gene SymbolDUSP13 to neXtProt (NX_Q9UII6)
DescriptionDual specificity protein phosphatase 13 isoform B
Chromosome10
Location10q22.2 (76854192 ~ 76868979) to Ensembl
Sequene Features : Isoforms 2, Variants 46, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.spermatogenesis
.meiotic nuclear division
.protein dephosphorylation
.protein tyrosine/serine/threonine phosphatase activity
.protein tyrosine phosphatase activity
.N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 46 0
2014-09-19protein level
2 37 0
2014-05-27protein level
2 37 0
2014-02-25protein level
2 36 0
2013-12-09protein level
2 25 0
2013-11-01protein level
2 25 0
2013-09-12protein level
2 25 0
2013-08-17protein level
3 33 0
2013-07-15protein level
3 29 0
2013-06-11protein level
3 29 0
2013-02-12protein level
4 15 0
2012-12-20protein level
4 16 0
2012-10-30protein level
4 20 0
2012-10-07protein level
4 20 0
2012-08-24protein level
4 19 0
2012-07-28protein level
4 19 0
2012-06-08protein level
4 22 0
2012-05-07protein level
4 22 0
2012-04-10protein level
4 22 0
2012-01-13protein level
4 12 0
2011-12-20protein level
4 12 0
2011-11-11protein level
4 12 0
2011-08-23protein level
4 12 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9UII6-1
0 10 0 22134.4765
NX_Q9UII6-4
1 10 2 27489.0766
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-749800,EBI-351935 LMNA  
  .negative regulation of extrinsic apoptotic signaling pathway
.regulation of protein localization to nucleus
.positive regulation of cell aging
  + 17 more...
.structural molecule activity .perinuclear region of cytoplasm
.nuclear membrane
.nuclear speck
  + 8 more...
2 EBI-749800,EBI-743290 HOOK2  
  .early endosome to late endosome transport
.protein transport
.endosome to lysosome transport
  + 3 more...
.identical protein binding .FHF complex
.microtubule
.centrosome
3 EBI-749800,EBI-751319 CARD9  
  .nucleotide-binding oligomerization domain containing signaling pathway
.defense response to virus
.defense response to Gram-positive bacterium
  + 17 more...
.CARD domain binding
.protein homodimerization activity
.plasma membrane
.cytosol
.cytoplasm
4 EBI-749800,EBI-749920 CALCOCO1  
  .positive regulation of transcription from RNA polymerase II promoter
.positive regulation of transcription, DNA-templated
.intracellular steroid hormone receptor signaling pathway
  + 3 more...
.armadillo repeat domain binding
.transcription regulatory region DNA binding
.sequence-specific DNA binding
  + 6 more...
.intracellular membrane-bounded organelle
.cytoplasm
.nucleus
.nuclear chromatin
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bone marrow41
eye4
heart78
liver4
muscle197
pancreas9
prostate10
testis13
Health State
TissuesTPM*
normal12
leukemia21
Developmental Stage
TissuesTPM*
adult5
fetus14
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
bone marrow3
esophagus7.4
heart muscle13.9
prostate6.8
testis32.3
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*613191, gene) Dual-specificity phosphatase 13; DUSP13OMIM


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