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> Protein (NX_Q9UIK4)
Protein (NX_Q9UIK4)
Protein
Gene SymbolDAPK2 to neXtProt (NX_Q9UIK4)
DescriptionDeath-associated protein kinase 2
Chromosome15
Location15q22.31 (64199235 ~ 64364232) to Ensembl
Sequene Features : Isoforms 2, Variants 65, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of intrinsic apoptotic signaling pathway
.protein autophosphorylation
.anoikis
  + 5 more...
.identical protein binding
.ATP binding
.calmodulin binding
  + 2 more...
.autophagic vacuole lumen
.cytoplasmic vesicle
.cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 65 3
2014-09-19protein level
2 50 3
2014-05-27protein level
2 50 3
2014-02-25protein level
2 50 3
2013-12-09protein level
2 37 3
2013-11-01protein level
2 36 3
2013-09-12protein level
2 36 3
2013-08-17protein level
2 36 3
2013-07-15protein level
2 27 3
2013-06-11protein level
2 27 3
2013-02-12protein level
2 21 3
2012-12-20protein level
2 20 3
2012-10-30protein level
2 24 3
2012-10-07protein level
2 24 3
2012-08-24protein level
2 22 3
2012-07-28protein level
2 22 3
2012-06-08protein level
2 32 3
2012-05-07protein level
2 32 3
2012-04-10protein level
2 32 3
2012-01-13protein level
2 12 3
2011-12-20protein level
2 19 3
2011-11-11protein level
1 17 3
2011-08-23protein level
1 17 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9UIK4-1
5 11 2 42871.2051
NX_Q9UIK4-2
7 11 2 55896.3743
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-9693115,EBI-492498 ATF4  
  .positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
.negative regulation of oxidative stress-induced neuron death
.intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
  + 21 more...
.protein heterodimerization activity
.transcription regulatory region DNA binding
.sequence-specific DNA binding
  + 9 more...
.CHOP-ATF4 complex
.ATF1-ATF4 transcription factor complex
.ATF4-CREB1 transcription factor complex
  + 8 more...
2 EBI-77154,EBI-10175124 FAM9B  
  .spermatid development .N/A .nucleoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood16
bone marrow20
brain12
connective tissue6
ear62
intestine47
lung8
lymph node11
mammary gland26
prostate5
skin9
stomach10
testis4
thyroid64
trachea19
uterus8
vascular38
Health State
TissuesTPM*
normal9
breast (mammary gland) tumor10
colorectal tumor8
gastrointestinal tumor8
glioma9
head and neck tumor14
leukemia21
lung tumor9
lymphoma13
non-neoplasia10
soft tissue/muscle tissue tumor7
uterine tumor11
Developmental Stage
TissuesTPM*
adult10
fetus3
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue18.3
adrenal gland3.8
appendix4.3
bone marrow14.9
cerebral cortex4.6
colon12.3
duodenum23.8
esophagus3.7
gallbladder3.3
heart muscle23.9
kidney3.1
liver2.2
lung30.4
lymph node4.5
ovary2.1
pancreas1.5
prostate7.2
salivary gland4.8
skin11.6
small intestine27.2
spleen8.9
stomach16.5
testis3.1
thyroid gland35.1
urinary bladder3.9
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)


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