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> Protein (NX_Q9UJY5)
Protein (NX_Q9UJY5)
Protein
Gene SymbolGGA1 to neXtProt (NX_Q9UJY5)
DescriptionADP-ribosylation factor-binding protein GGA1
Chromosome22
Location22q13.1 (38004481 ~ 38029571) to Ensembl
Sequene Features : Isoforms 6, Variants 69, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of protein catabolic process
.vesicle-mediated transport
.intracellular protein transport
.N/A .intracellular membrane-bounded organelle
.clathrin adaptor complex
.membrane
  + 3 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
6 69 7
2014-09-19protein level
5 49 7
2014-05-27protein level
5 49 7
2014-02-25protein level
5 49 7
2013-12-09protein level
5 28 8
2013-11-01protein level
5 26 6
2013-09-12protein level
5 26 6
2013-08-17protein level
5 26 6
2013-07-15protein level
5 16 1
2013-06-11protein level
5 16 1
2013-02-12protein level
5 8 11
2012-12-20protein level
5 8 11
2012-10-30protein level
5 14 11
2012-10-07protein level
5 14 3
2012-08-24protein level
5 14 3
2012-07-28protein level
5 14 3
2012-06-08protein level
5 39 3
2012-05-07protein level
5 38 3
2012-04-10protein level
5 38 3
2012-01-13protein level
2 33 3
2011-12-20protein level
2 33 3
2011-11-11protein level
2 33 3
2011-08-23protein level
2 33 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9UJY5-1
0 19 0 70339.8437
NX_Q9UJY5-2
1 18 0 66520.8397
NX_Q9UJY5-3
0 16 0 62098.8282
NX_Q9UJY5-4
1 17 0 61340.383
NX_Q9UJY5-5
0 4 0 9962.866
NX_Q9UJY5-6
0 20 0 72231.8067
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-447141,EBI-740402 DTNB  
  .N/A .zinc ion binding .synapse
.cytoplasm
2 EBI-447141,EBI-413034 UBB  
  .positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator
.regulation of neuron death
.programmed necrotic cell death
  + 96 more...
.N/A .extracellular exosome
.neuronal cell body
.neuron projection
  + 6 more...
3 EBI-447141,EBI-1048580 IGF2R  
  .insulin-like growth factor receptor signaling pathway
.positive regulation of apoptotic process
.response to retinoic acid
  + 6 more...
.phosphoprotein binding
.identical protein binding
.mannose binding
  + 6 more...
.extracellular exosome
.perinuclear region of cytoplasm
.trans-Golgi network transport vesicle
  + 13 more...
4 EBI-447141,EBI-447043 RABEP1  
  .membrane fusion
.vesicle-mediated transport
.protein transport
  + 2 more...
.protein homodimerization activity
.GTPase activator activity
.recycling endosome
.intracellular membrane-bounded organelle
.endocytic vesicle
  + 2 more...
5 EBI-447141,EBI-358882 MON2  
  .positive regulation of GTPase activity
.actin cytoskeleton organization
.vesicle-mediated transport
  + 2 more...
.ARF guanyl-nucleotide exchange factor activity .extracellular exosome
.trans-Golgi network
6 EBI-447141,EBI-747505 C1orf216  
  .N/A .N/A .N/A
7 EBI-447141,EBI-1057058 SORT1  
  .negative regulation of lipoprotein lipase activity
.plasma membrane to endosome transport
.neurotrophin TRK receptor signaling pathway
  + 15 more...
.nerve growth factor binding
.neurotensin receptor activity, non-G-protein coupled
.enzyme binding
.nerve growth factor receptor activity
.perinuclear region of cytoplasm
.Golgi cisterna membrane
.nuclear membrane
  + 12 more...
8 EBI-447141,EBI-396669 RNF11  
  .protein autoubiquitination
.protein ubiquitination involved in ubiquitin-dependent protein catabolic process
.zinc ion binding
.ubiquitin-protein transferase activity
.DNA binding
.extracellular exosome
.recycling endosome
.early endosome
  + 2 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland121
ascites1079
blood81
bone41
bone marrow20
brain102
cervix61
connective tissue40
embryonic tissue117
esophagus49
eye81
heart22
intestine77
kidney71
larynx42
liver34
lung50
lymph112
lymph node44
mammary gland132
mouth120
muscle28
nerve64
ovary9
pancreas56
pharynx24
pituitary gland60
placenta67
prostate47
salivary gland49
skin71
spleen224
stomach31
testis475
thymus125
thyroid107
tonsil176
trachea19
uterus51
vascular38
Health State
TissuesTPM*
normal88
bladder carcinoma113
breast (mammary gland) tumor128
cervical tumor28
chondrosarcoma48
colorectal tumor44
gastrointestinal tumor388
germ cell tumor102
glioma130
head and neck tumor74
kidney tumor101
leukemia116
liver tumor41
lung tumor68
lymphoma290
non-neoplasia72
pancreatic tumor38
primitive neuroectodermal tumor of the CNS299
prostate cancer38
retinoblastoma64
skin tumor103
soft tissue/muscle tissue tumor39
uterine tumor44
Developmental Stage
TissuesTPM*
adult68
embryoid body100
blastocyst162
neonate96
fetus70
juvenile251
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue18.6
adrenal gland33.7
appendix34.9
bone marrow30.9
cerebral cortex27.8
colon23.9
duodenum33.7
esophagus25.1
gallbladder28.6
heart muscle17.9
kidney21.7
liver10.7
lung29.2
lymph node37.5
ovary30.5
pancreas14.4
placenta25.6
prostate29.2
salivary gland29.3
skin38.4
small intestine28.6
spleen42.7
stomach34.6
testis154.4
thyroid gland35.9
urinary bladder25.7
Tissues
TissuesExpression level
adrenal glandMedium
appendixMedium
bone marrowLow
breastMedium
bronchusMedium
cerebellumMedium
cerebral cortexLow
cervix, uterineMedium
colonMedium
duodenumHigh
endometrium 1Medium
endometrium 2Medium
epididymisMedium
esophagusHigh
fallopian tubeMedium
gallbladderMedium
heart muscleLow
hippocampusLow
kidneyMedium
lateral ventricleLow
lungMedium
lymph nodeMedium
nasopharynxMedium
oral mucosaMedium
ovaryLow
pancreasMedium
placentaHigh
prostateMedium
rectumMedium
salivary glandMedium
seminal vesicleMedium
skin 1Medium
skin 2Low
small intestineMedium
smooth muscleMedium
soft tissue 1Medium
spleenMedium
stomach 1Medium
stomach 2Medium
testisMedium
thyroid glandMedium
tonsilHigh
urinary bladderHigh
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*606004, gene) Golgi-associated, gamma-adaptin ear-containing, arf-binding proteinOMIM


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