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> Protein (NX_Q9UK45)
Protein (NX_Q9UK45)
Protein
Gene SymbolLSM7 to neXtProt (NX_Q9UK45)
DescriptionU6 snRNA-associated Sm-like protein LSm7
Chromosome19
Location19p13.3 (2321516 ~ 2328619) to Ensembl
Sequene Features : Isoforms 1, Variants 1, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
.gene expression
.mRNA splicing, via spliceosome
.nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
.U6 snRNA binding .cytosol
.small nucleolar ribonucleoprotein complex
.spliceosomal complex
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 1 5
2014-09-19protein level
1 1 5
2014-05-27protein level
1 1 5
2014-02-25protein level
1 1 5
2013-12-09protein level
1 1 5
2013-11-01protein level
1 1 4
2013-09-12protein level
1 1 3
2013-08-17protein level
1 1 3
2013-07-15protein level
1 2 2
2013-06-11protein level
1 2 2
2013-02-12protein level
1 0 0
2012-12-20protein level
1 0 0
2012-10-30protein level
1 0 0
2012-10-07protein level
1 0 0
2012-08-24protein level
1 0 0
2012-07-28protein level
1 0 0
2012-06-08protein level
1 0 0
2012-05-07protein level
1 0 0
2012-04-10protein level
1 0 0
2012-01-13protein level
1 0 0
2011-12-20protein level
1 0 0
2011-11-11protein level
1 0 0
2011-08-23protein level
1 0 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9UK45-1
4 0 0 11594.9736
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-348372,EBI-624252 TACC1  
  .cell division
.regulation of microtubule-based process
.interkinetic nuclear migration
  + 5 more...
.N/A .intermediate filament cytoskeleton
.microtubule cytoskeleton
.microtubule organizing center
  + 2 more...
2 EBI-348372,EBI-348239 LSM3  
  .exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
.gene expression
.mRNA processing
  + 2 more...
.poly(A) RNA binding .catalytic step 2 spliceosome
.cytosol
.nucleus
3 EBI-348372,EBI-373310 LSM6  
  .exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
.maturation of SSU-rRNA
.gene expression
  + 4 more...
.poly(A) RNA binding .extracellular exosome
.U4/U6 x U5 tri-snRNP complex
.small nuclear ribonucleoprotein complex
  + 6 more...
4 EBI-348372,EBI-372789 SNRPD3  
  .ncRNA metabolic process
.mRNA 3'-end processing
.gene expression
  + 7 more...
.histone pre-mRNA DCP binding
.poly(A) RNA binding
.enzyme binding
.catalytic step 2 spliceosome
.extracellular exosome
.SMN-Sm protein complex
  + 11 more...
5 EBI-348372,EBI-742054 DDIT4L  
  .negative regulation of signal transduction .N/A .cytoplasm
6 EBI-348372,EBI-347416 LSM2  
  .exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
.gene expression
.RNA splicing
  + 2 more...
.poly(A) RNA binding
.Ral GTPase binding
.U6 snRNA binding
.catalytic step 2 spliceosome
.cytosol
.nucleoplasm
7 EBI-348372,EBI-373007 LSM5  
  .exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
.gene expression
.RNA splicing
  + 2 more...
.RNA binding .cytosol
.spliceosomal complex
.nucleus
8 EBI-348372,EBI-372521 LSM4  
  .activation of mitophagy in response to mitochondrial depolarization
.exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
.gene expression
  + 4 more...
.poly(A) RNA binding .small nuclear ribonucleoprotein complex
.cytosol
.U6 snRNP
.spliceosomal complex
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
ascites50
blood8
bone13
bone marrow41
brain22
connective tissue20
embryonic tissue37
esophagus49
eye47
heart44
intestine56
kidney42
liver43
lung29
lymph node77
mammary gland26
mouth15
ovary49
pancreas46
parathyroid97
pituitary gland60
placenta3
prostate47
skin18
spleen56
stomach20
testis9
thymus12
thyroid21
tonsil176
trachea19
uterus25
vascular38
Health State
TissuesTPM*
normal26
adrenal tumor79
chondrosarcoma48
colorectal tumor26
esophageal tumor57
gastrointestinal tumor50
germ cell tumor30
glioma55
head and neck tumor14
kidney tumor43
leukemia42
liver tumor31
lung tumor48
non-neoplasia10
ovarian tumor13
pancreatic tumor57
primitive neuroectodermal tumor of the CNS7
prostate cancer38
retinoblastoma21
skin tumor31
soft tissue/muscle tissue tumor15
uterine tumor11
Developmental Stage
TissuesTPM*
adult27
embryoid body71
blastocyst16
fetus17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue30.4
adrenal gland29.2
appendix53.1
bone marrow66.1
cerebral cortex26.3
colon60.5
duodenum57.9
esophagus22.9
gallbladder25.3
heart muscle18.2
kidney32.9
liver24.9
lung26
lymph node67.6
ovary38
pancreas13.6
placenta38.3
prostate36.4
salivary gland32
skin31.7
small intestine50.1
spleen60.5
stomach50.6
testis29.7
thyroid gland18.9
urinary bladder28.9
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*607287, gene) Lsm7 protein; LSM7OMIM


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