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> Protein (NX_Q9UK58)
Protein (NX_Q9UK58)
Protein
Gene SymbolCCNL1 to neXtProt (NX_Q9UK58)
DescriptionCyclin-L1
Chromosome3
Location3q25.31 (156864297 ~ 156878549) to Ensembl
Sequene Features : Isoforms 3, Variants 50, PTMs 10 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.RNA processing
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.regulation of cyclin-dependent protein serine/threonine kinase activity
.N/A .nuclear speck
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 50 10
2014-09-19protein level
3 37 10
2014-05-27protein level
3 37 10
2014-02-25protein level
3 37 10
2013-12-09protein level
3 31 10
2013-11-01protein level
3 30 10
2013-09-12protein level
3 30 10
2013-08-17protein level
3 30 10
2013-07-15protein level
3 15 10
2013-06-11protein level
3 15 10
2013-02-12protein level
3 4 13
2012-12-20protein level
3 4 13
2012-10-30protein level
3 3 13
2012-10-07protein level
3 3 11
2012-08-24protein level
3 0 11
2012-07-28protein level
3 0 11
2012-06-08protein level
3 2 11
2012-05-07protein level
3 11 11
2012-04-10protein level
3 11 11
2012-01-13protein level
3 4 11
2011-12-20protein level
3 4 11
2011-11-11protein level
3 4 10
2011-08-23protein level
3 4 10
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9UK58-1
7 8 2 59597.0131
NX_Q9UK58-4
1 8 2 25392.2225
NX_Q9UK58-5
1 7 0 18310.4233
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2836773,EBI-743771 APPBP2  
  .intracellular transport
.metabolic process
.intracellular protein transport
.microtubule motor activity .cytoplasmic vesicle membrane
.microtubule associated complex
.microtubule
  + 2 more...
2 EBI-2836773,EBI-1105213 TFIP11  
  .biomineral tissue development
.RNA processing
.regulation of transcription, DNA-templated
  + 2 more...
.DNA binding .catalytic step 2 spliceosome
.U2-type post-mRNA release spliceosomal complex
.nuclear speck
  + 3 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland60
ascites50
bladder167
blood286
bone83
bone marrow225
brain70
cervix41
connective tissue127
embryonic tissue103
esophagus248
eye90
heart33
intestine90
kidney66
larynx42
liver58
lung137
lymph67
lymph node178
mammary gland66
mouth105
muscle103
nerve193
ovary147
pancreas70
pharynx122
pituitary gland181
placenta88
prostate100
skin75
spleen243
stomach94
testis64
thymus363
thyroid21
trachea231
uterus168
vascular96
Health State
TissuesTPM*
normal109
adrenal tumor79
bladder carcinoma56
breast (mammary gland) tumor32
cervical tumor28
chondrosarcoma132
colorectal tumor97
esophageal tumor289
gastrointestinal tumor92
germ cell tumor64
glioma9
head and neck tumor97
kidney tumor29
leukemia328
liver tumor20
lung tumor38
lymphoma41
non-neoplasia155
ovarian tumor157
pancreatic tumor38
primitive neuroectodermal tumor of the CNS39
prostate cancer105
retinoblastoma21
skin tumor47
soft tissue/muscle tissue tumor31
uterine tumor133
Developmental Stage
TissuesTPM*
adult118
embryoid body128
blastocyst97
neonate64
fetus82
infant85
juvenile71
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue92.3
adrenal gland85.6
appendix113.2
bone marrow671.8
cerebral cortex29.6
colon48.7
duodenum88
esophagus45.3
gallbladder100.2
heart muscle21.5
kidney33.9
liver50
lung95.8
lymph node111.8
ovary76.9
pancreas39.6
placenta63
prostate68.7
salivary gland45
skin73.3
small intestine110.4
spleen103.5
stomach69
testis32.8
thyroid gland55.8
urinary bladder60.3
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*613384, gene) Cyclin l1; CCNL1OMIM


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