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> Protein (NX_Q9UKF7)
Protein (NX_Q9UKF7)
Protein
Gene SymbolPITPNC1 to neXtProt (NX_Q9UKF7)
DescriptionCytoplasmic phosphatidylinositol transfer protein 1
Chromosome17
Location17q24.2 (65373575 ~ 65693372) to Ensembl
Sequene Features : Isoforms 2, Variants 36, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.phospholipid transport
.signal transduction
.phosphatidylinositol transporter activity
.lipid binding
.cytoplasm
.nucleoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 36 1
2014-09-19protein level
2 27 1
2014-05-27protein level
2 27 1
2014-02-25protein level
2 27 1
2013-12-09protein level
2 25 1
2013-11-01protein level
2 25 1
2013-09-12protein level
2 25 2
2013-08-17protein level
2 25 2
2013-07-15protein level
2 16 2
2013-06-11protein level
2 16 2
2013-02-12protein level
2 6 1
2012-12-20protein level
2 7 1
2012-10-30protein level
2 7 1
2012-10-07protein level
2 7 1
2012-08-24protein level
2 2 1
2012-07-28protein level
2 0 1
2012-06-08protein level
2 3 1
2012-05-07protein level
2 3 1
2012-04-10protein level
2 3 1
2012-01-13protein level
2 3 1
2011-12-20protein level
2 3 1
2011-11-11protein level
2 3 1
2011-08-23protein level
2 3 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9UKF7-1
5 12 0 38363.0755
NX_Q9UKF7-2
2 12 0 31762.3174
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-749241,EBI-741181 AGTRAP  
  .regulation of blood pressure
.response to hypoxia
.angiotensin type II receptor activity .intracellular membrane-bounded organelle
.cytoplasmic vesicle membrane
.integral component of membrane
  + 6 more...
2 EBI-749241,EBI-2548702 CMTM5  
  .negative regulation of myoblast differentiation
.chemotaxis
.N/A .integral component of membrane
.extracellular space
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
ascites75
blood8
bone41
bone marrow61
brain34
cervix20
connective tissue46
embryonic tissue51
eye129
heart55
intestine17
kidney18
larynx85
liver4
lung17
lymph22
lymph node155
mammary gland19
mouth45
nerve64
ovary29
pancreas84
parathyroid48
pharynx24
pituitary gland60
placenta7
prostate15
skin56
spleen18
stomach20
testis6
thymus12
tonsil117
uterus21
Health State
TissuesTPM*
normal44
breast (mammary gland) tumor21
chondrosarcoma48
colorectal tumor8
gastrointestinal tumor50
germ cell tumor37
glioma46
head and neck tumor22
kidney tumor29
leukemia95
lung tumor19
lymphoma55
non-neoplasia31
ovarian tumor39
pancreatic tumor38
primitive neuroectodermal tumor of the CNS15
skin tumor95
soft tissue/muscle tissue tumor47
uterine tumor11
Developmental Stage
TissuesTPM*
adult44
blastocyst16
fetus35
infant85
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue16.1
adrenal gland9
appendix18.7
bone marrow9.3
cerebral cortex25.4
colon8
duodenum3.7
esophagus13
gallbladder17.3
heart muscle10.6
kidney13.5
liver9.5
lung10.2
lymph node29.4
ovary16.3
pancreas8.7
placenta14
prostate10.2
salivary gland13.6
skin1.9
small intestine5.9
spleen12.9
stomach10.5
testis4.8
thyroid gland14.8
urinary bladder18.4
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*605134, gene) Phosphatidylinositol transfer protein, cytoplasmic, 1; PITPNC1OMIM


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