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> Protein (NX_Q9UL15)
Protein (NX_Q9UL15)
Protein
Gene SymbolBAG5 to neXtProt (NX_Q9UL15)
DescriptionBAG family molecular chaperone regulator 5
Chromosome14
Location14q32.33 (104022881 ~ 104029168) to Ensembl
Sequene Features : Isoforms 2, Variants 43, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
.regulation of cellular response to heat
.regulation of inclusion body assembly
  + 7 more...
.chaperone binding
.ubiquitin protein ligase binding
.protein kinase binding
.perinuclear region of cytoplasm
.inclusion body
.membrane
  + 3 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 43 1
2014-09-19protein level
2 37 1
2014-05-27protein level
2 37 1
2014-02-25protein level
2 37 1
2013-12-09protein level
2 31 1
2013-11-01protein level
2 27 1
2013-09-12protein level
2 27 1
2013-08-17protein level
2 27 1
2013-07-15protein level
2 23 0
2013-06-11protein level
2 23 0
2013-02-12protein level
2 11 2
2012-12-20protein level
2 11 2
2012-10-30protein level
2 15 2
2012-10-07protein level
2 15 1
2012-08-24protein level
2 8 1
2012-07-28protein level
2 8 1
2012-06-08protein level
2 8 1
2012-05-07protein level
2 8 1
2012-04-10protein level
2 8 1
2012-01-13protein level
2 2 1
2011-12-20protein level
2 2 1
2011-11-11protein level
2 2 1
2011-08-23protein level
2 2 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9UL15-1
1 19 0 51167.5599
NX_Q9UL15-2
3 19 0 55991.8102
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-356517,EBI-629985 HSPA1A  
  .N/A .N/A .N/A
2 EBI-356517,EBI-719493 TRIM27  
  .negative regulation of viral release from host cell
.negative regulation of interleukin-2 secretion
.negative regulation of calcium ion import
  + 17 more...
.metal ion binding
.ligase activity
.zinc ion binding
  + 4 more...
.nuclear membrane
.PML body
.membrane
  + 6 more...
3 EBI-356517,EBI-1050422 LRRK1  
  .positive regulation of intracellular signal transduction
.negative regulation of peptidyl-tyrosine phosphorylation
.positive regulation of peptidyl-tyrosine phosphorylation
  + 3 more...
.metal ion binding
.identical protein binding
.GTP binding
  + 2 more...
.mitochondrion
.cytoplasm
4 EBI-356517,EBI-5323863 LRRK2  
  .negative regulation of peroxidase activity
.regulation of synaptic vesicle exocytosis
.regulation of branching morphogenesis of a nerve
  + 64 more...
.protein kinase A binding
.ion channel binding
.protein homodimerization activity
  + 18 more...
.extracellular exosome
.membrane raft
.perikaryon
  + 25 more...
5 EBI-356517,EBI-749265 CCDC155  
  .chromosome localization to nuclear envelope involved in homologous chromosome segregation
.oogenesis
.spermatogenesis
  + 2 more...
.N/A .integral component of membrane
.nuclear outer membrane
.lateral element
.chromosome, telomeric region
6 EBI-356517,EBI-744695 BANP  
  .negative regulation of protein catabolic process
.protein localization to nucleus
.chromatin modification
  + 4 more...
.DNA binding .nucleoplasm
7 EBI-356517,EBI-726822 FAM118B  
  .N/A .N/A .Cajal body
8 EBI-356517,EBI-741515 THAP1  
  .regulation of mitotic cell cycle
.cell cycle
.regulation of transcription, DNA-templated
  + 2 more...
.sequence-specific DNA binding
.identical protein binding
.zinc ion binding
.PML body
.nucleus
9 EBI-356517,EBI-742610 MAD1L1  
  .regulation of metaphase plate congression
.cell division
.small GTPase mediated signal transduction
  + 4 more...
.N/A .mitotic spindle
.actin cytoskeleton
.cytosol
  + 6 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue155
ascites25
bladder100
blood40
bone27
bone marrow82
brain69
cervix61
connective tissue40
embryonic tissue28
eye23
heart22
intestine47
kidney61
liver73
lung35
lymph22
lymph node89
mammary gland52
mouth60
muscle65
ovary88
parathyroid97
pharynx98
pituitary gland121
placenta45
prostate47
skin33
spleen93
stomach10
testis236
thymus87
thyroid21
trachea154
umbilical cord72
uterus64
vascular38
Health State
TissuesTPM*
normal64
bladder carcinoma113
breast (mammary gland) tumor75
cervical tumor86
chondrosarcoma48
colorectal tumor26
gastrointestinal tumor25
germ cell tumor45
glioma18
head and neck tumor44
kidney tumor58
leukemia42
liver tumor72
lung tumor29
lymphoma27
non-neoplasia51
ovarian tumor118
prostate cancer48
retinoblastoma43
skin tumor15
soft tissue/muscle tissue tumor7
uterine tumor33
Developmental Stage
TissuesTPM*
adult52
embryoid body28
blastocyst32
neonate32
fetus57
juvenile71
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue20.5
adrenal gland11.8
appendix15.7
bone marrow17
cerebral cortex15.6
colon15.4
duodenum10.8
esophagus21.2
gallbladder13.7
heart muscle10.4
kidney14.2
liver5.8
lung15.6
lymph node17.1
ovary11.5
pancreas6.1
placenta14.9
prostate13.5
salivary gland11.8
skin15.9
small intestine10.9
spleen16.6
stomach13.9
testis118.7
thyroid gland24.6
urinary bladder16.3
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*603885, gene) Bcl2-associated athanogene 5; BAG5OMIM


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