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> Protein (NX_Q9UL18)
Protein (NX_Q9UL18)
Protein
Gene SymbolAGO1 to neXtProt (NX_Q9UL18)
DescriptionProtein argonaute-1
Chromosome1
Location1p34.3 (36335409 ~ 36395211) to Ensembl
Sequene Features : Isoforms 1, Variants 10, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.phosphatidylinositol-mediated signaling
.neurotrophin TRK receptor signaling pathway
.positive regulation of transcription from RNA polymerase II promoter
  + 15 more...
.pre-miRNA binding
.poly(A) RNA binding
.miRNA binding
  + 6 more...
.RISC-loading complex
.micro-ribonucleoprotein complex
.ribonucleoprotein complex
  + 7 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 10 2
2014-09-19protein level
1 54 2
2014-05-27protein level
1 54 3
2014-02-25protein level
1 54 3
2013-12-09protein level
1 46 3
2013-11-01protein level
1 45 3
2013-09-12protein level
1 45 3
2013-08-17protein level
1 45 3
2013-07-15protein level
1 31 2
2013-06-11protein level
1 31 2
2013-02-12protein level
1 11 2
2012-12-20protein level
1 11 2
2012-10-30protein level
1 12 2
2012-10-07protein level
1 12 2
2012-08-24protein level
1 11 2
2012-07-28protein level
1 11 2
2012-06-08protein level
1 12 2
2012-05-07protein level
1 4 2
2012-04-10protein level
1 4 2
2012-01-13protein level
1 8 2
2011-12-20protein level
1 8 2
2011-11-11protein level
1 8 2
2011-08-23protein level
1 8 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9UL18-1
26 0 17 97151.8393
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-527363,EBI-358808 IPO8  
  .gene expression
.signal transduction
.intracellular protein transport
.Ran GTPase binding .cytosol
.nucleoplasm
2 EBI-527363,EBI-352572 HSP90AB1  
  .regulation of cellular response to heat
.fibril organization
.cellular response to interleukin-4
  + 14 more...
.poly(A) RNA binding
.TPR domain binding
.nitric-oxide synthase regulator activity
  + 4 more...
.extracellular exosome
.melanosome
.membrane
  + 4 more...
3 EBI-527363,EBI-2269715 TNRC6A  
  .phosphatidylinositol-mediated signaling
.neurotrophin TRK receptor signaling pathway
.innate immune response
  + 9 more...
.poly(A) RNA binding
.nucleotide binding
.micro-ribonucleoprotein complex
.cytosol
.nucleoplasm
.cytoplasmic mRNA processing body
4 EBI-527363,EBI-395506 DICER1  
  .positive regulation of miRNA metabolic process
.RNA phosphodiester bond hydrolysis, endonucleolytic
.hair follicle cell proliferation
  + 47 more...
.pre-miRNA binding
.metal ion binding
.miRNA binding
  + 6 more...
.RISC-loading complex
.micro-ribonucleoprotein complex
.ARC complex
  + 8 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
ascites25
blood57
bone13
bone marrow20
brain3
cervix41
connective tissue40
ear124
embryonic tissue4
eye23
heart44
intestine4
kidney18
liver4
lung8
lymph22
lymph node44
mammary gland19
muscle37
ovary29
pancreas9
placenta24
prostate10
skin33
spleen18
stomach10
testis4
thymus12
thyroid107
uterus4
Health State
TissuesTPM*
normal6
breast (mammary gland) tumor32
cervical tumor57
chondrosarcoma12
colorectal tumor71
gastrointestinal tumor8
germ cell tumor41
glioma46
head and neck tumor22
kidney tumor43
leukemia74
liver tumor52
lung tumor9
lymphoma13
non-neoplasia10
ovarian tumor39
pancreatic tumor19
primitive neuroectodermal tumor of the CNS7
prostate cancer48
retinoblastoma21
skin tumor47
soft tissue/muscle tissue tumor23
uterine tumor44
Developmental Stage
TissuesTPM*
adult3
embryoid body71
blastocyst48
fetus3
juvenile89
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue5.1
adrenal gland6.3
appendix7.6
bone marrow4.3
cerebral cortex5.7
colon6.7
duodenum5.7
esophagus6.1
gallbladder5
heart muscle5.7
kidney5.9
liver2.3
lung5.7
lymph node6.2
ovary8
pancreas2.8
placenta4.8
prostate6.3
salivary gland4.4
skin7.1
small intestine6.6
spleen8
stomach6.1
testis6
thyroid gland6.6
urinary bladder6.7
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Disease
No.Disease DescriptionRef.
1(*606228, gene) Eukaryotic translation initiation factor 2c, subunit 1; EIF2C1OMIM


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