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> Protein (NX_Q9UL25)
Protein (NX_Q9UL25)
Protein
Gene SymbolRAB21 to neXtProt (NX_Q9UL25)
DescriptionRas-related protein Rab-21
Chromosome12
Location12q21.1 (72148654 ~ 72184699) to Ensembl
Sequene Features : Isoforms 1, Variants 26, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of early endosome to late endosome transport
.positive regulation of receptor-mediated endocytosis
.Rab protein signal transduction
  + 3 more...
.GDP binding
.GTP binding
.GTPase activity
.cytoplasmic side of early endosome membrane
.extracellular exosome
.Golgi cisterna membrane
  + 8 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 26 6
2014-09-19protein level
1 21 6
2014-05-27protein level
1 21 6
2014-02-25protein level
1 21 6
2013-12-09protein level
1 16 6
2013-11-01protein level
1 16 6
2013-09-12protein level
1 16 6
2013-08-17protein level
1 16 6
2013-07-15protein level
1 8 5
2013-06-11protein level
1 8 5
2013-02-12protein level
1 4 4
2012-12-20protein level
1 5 4
2012-10-30protein level
1 6 4
2012-10-07protein level
1 6 4
2012-08-24protein level
1 5 4
2012-07-28protein level
1 5 4
2012-06-08protein level
1 7 4
2012-05-07protein level
1 7 4
2012-04-10protein level
1 7 4
2012-01-13protein level
1 4 4
2011-12-20protein level
1 4 4
2011-11-11protein level
1 4 4
2011-08-23protein level
1 4 4
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9UL25-1
12 0 0 24332.1857
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1056039,EBI-741243 APPL1  
  .extrinsic apoptotic signaling pathway in absence of ligand
.extrinsic apoptotic signaling pathway
.regulation of establishment of protein localization to plasma membrane
  + 7 more...
.protein kinase B binding
.identical protein binding
.extracellular exosome
.early endosome membrane
.vesicle membrane
  + 4 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
bladder66
blood32
bone41
bone marrow20
brain18
connective tissue6
embryonic tissue42
eye23
heart33
intestine47
kidney42
liver38
lung14
lymph45
lymph node66
mammary gland19
mouth15
muscle47
nerve64
ovary9
pancreas32
parathyroid48
pituitary gland121
placenta91
prostate52
skin23
stomach31
testis25
thymus25
trachea38
uterus25
Health State
TissuesTPM*
normal36
bladder carcinoma56
breast (mammary gland) tumor32
chondrosarcoma24
colorectal tumor26
gastrointestinal tumor25
germ cell tumor18
glioma37
head and neck tumor7
kidney tumor43
leukemia31
lung tumor19
lymphoma55
ovarian tumor13
pancreatic tumor28
primitive neuroectodermal tumor of the CNS47
prostate cancer77
skin tumor31
soft tissue/muscle tissue tumor31
uterine tumor33
Developmental Stage
TissuesTPM*
adult34
embryoid body57
blastocyst32
fetus34
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue37.3
adrenal gland49.5
appendix31.4
bone marrow35.7
cerebral cortex32.4
colon32.6
duodenum21.9
esophagus40.5
gallbladder36.4
heart muscle63.9
kidney51.5
liver26
lung30.1
lymph node30.8
ovary28.3
pancreas13.9
placenta36.4
prostate31.7
salivary gland21.7
skin21.5
small intestine21.6
spleen26.1
stomach28.3
testis24
thyroid gland40.9
urinary bladder39
Tissues
TissuesExpression level
adrenal glandHigh
appendixMedium
bone marrowMedium
breastMedium
bronchusMedium
cerebellumHigh
cerebral cortexMedium
cervix, uterineMedium
colonMedium
duodenumMedium
endometrium 1Medium
endometrium 2Medium
epididymisMedium
esophagusMedium
fallopian tubeMedium
gallbladderHigh
heart muscleMedium
hippocampusMedium
kidneyHigh
lateral ventricleMedium
liverMedium
lungMedium
lymph nodeMedium
nasopharynxMedium
oral mucosaLow
ovaryMedium
pancreasMedium
parathyroid glandMedium
placentaMedium
prostateMedium
rectumMedium
salivary glandHigh
seminal vesicleMedium
skeletal muscleMedium
skin 1Medium
skin 2Medium
small intestineMedium
smooth muscleMedium
soft tissue 1Low
soft tissue 2Medium
spleenMedium
stomach 1Medium
stomach 2Medium
testisHigh
thyroid glandMedium
tonsilMedium
urinary bladderMedium
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*612398, gene) Rab-associated protein rab21; RAB21OMIM


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