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> Protein (NX_Q9UL33)
Protein (NX_Q9UL33)
Protein
Gene SymbolTRAPPC2L to neXtProt (NX_Q9UL33)
DescriptionTrafficking protein particle complex subunit 2-like protein
Chromosome16
Location16q24.3 (88922628 ~ 88929094) to Ensembl
Sequene Features : Isoforms 2, Variants 23, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.ER to Golgi vesicle-mediated transport .N/A .perinuclear region of cytoplasm
.Golgi apparatus
.endoplasmic reticulum
.cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 23 1
2014-09-19protein level
2 18 1
2014-05-27protein level
2 18 1
2014-02-25protein level
2 18 1
2013-12-09protein level
2 13 1
2013-11-01protein level
2 12 0
2013-09-12protein level
2 12 0
2013-08-17protein level
2 12 0
2013-07-15protein level
2 10 0
2013-06-11protein level
2 10 0
2013-02-12protein level
2 7 0
2012-12-20protein level
2 7 0
2012-10-30protein level
2 8 0
2012-10-07protein level
2 8 0
2012-08-24protein level
2 8 0
2012-07-28protein level
2 8 0
2012-06-08protein level
2 8 0
2012-05-07protein level
2 7 0
2012-04-10protein level
2 7 0
2012-01-13protein level
2 6 0
2011-12-20protein level
2 6 0
2011-11-11protein level
2 6 0
2011-08-23protein level
2 6 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9UL33-1
0 9 0 16134.8786
NX_Q9UL33-2
0 9 0 16047.8468
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-747601,EBI-743566 TRAPPC3  
  .vesicle-mediated transport .N/A .Golgi apparatus
.endoplasmic reticulum
2 EBI-747601,EBI-533224 TCF4  
  .protein-DNA complex assembly
.positive regulation of transcription from RNA polymerase II promoter
.positive regulation of transcription, DNA-templated
  + 3 more...
.E-box binding
.protein heterodimerization activity
.bHLH transcription factor binding
  + 9 more...
.transcription factor complex
.nucleus
3 EBI-747601,EBI-307352 REL  
  .negative regulation of neuron death
.positive regulation of transcription from RNA polymerase II promoter
.innate immune response
  + 10 more...
.sequence-specific DNA binding transcription factor activity
.chromatin binding
.RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.RNA polymerase II distal enhancer sequence-specific DNA binding
.I-kappaB/NF-kappaB complex
.cytosol
.transcription factor complex
  + 2 more...
4 EBI-747601,EBI-742327 TRIP6  
  .focal adhesion assembly
.positive regulation of cell migration
.release of cytoplasmic sequestered NF-kappaB
  + 2 more...
.thyroid hormone receptor binding
.poly(A) RNA binding
.kinase binding
  + 2 more...
.focal adhesion
.plasma membrane
.cytoskeleton
  + 2 more...
5 EBI-747601,EBI-10181988 CEP57L1  
  .microtubule anchoring .N/A .microtubule
.microtubule organizing center
.cytoplasm
6 EBI-747601,EBI-10284498 REPS1  
  .receptor-mediated endocytosis .SH3 domain binding
.calcium ion binding
.coated pit
.plasma membrane
7 EBI-747601,EBI-2548012 BLZF1  
  .Golgi to plasma membrane protein transport
.cell proliferation
.Golgi organization
  + 3 more...
.ubiquitin protein ligase binding
.enzyme binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.Golgi lumen
.cytoplasm
.nucleoplasm
  + 2 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland333
ascites50
bladder33
blood98
bone27
bone marrow102
brain53
cervix20
connective tissue26
embryonic tissue42
esophagus49
eye62
heart67
intestine51
kidney47
larynx42
liver19
lung47
lymph node100
mammary gland39
mouth15
muscle65
ovary29
pancreas9
parathyroid194
pharynx24
pituitary gland121
placenta74
prostate58
salivary gland98
skin28
spleen37
testis45
thymus12
thyroid64
trachea19
umbilical cord217
uterus47
Health State
TissuesTPM*
normal56
adrenal tumor158
breast (mammary gland) tumor64
cervical tumor28
chondrosarcoma24
colorectal tumor35
esophageal tumor57
gastrointestinal tumor16
germ cell tumor41
glioma130
head and neck tumor44
kidney tumor58
leukemia84
liver tumor20
lung tumor9
lymphoma83
non-neoplasia31
pancreatic tumor9
primitive neuroectodermal tumor of the CNS23
prostate cancer38
retinoblastoma107
skin tumor23
soft tissue/muscle tissue tumor31
uterine tumor55
Developmental Stage
TissuesTPM*
adult54
blastocyst97
neonate96
fetus53
infant42
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue26.9
adrenal gland62.3
appendix25.8
bone marrow25.6
cerebral cortex29.6
colon29.3
duodenum20
esophagus26.1
gallbladder30.5
heart muscle39.3
kidney33.5
liver18.3
lung26.4
lymph node40.2
ovary42.4
pancreas17.1
placenta23
prostate24.5
salivary gland25.4
skin30
small intestine20.1
spleen30.1
stomach26.4
testis50.3
thyroid gland34.2
urinary bladder30.8
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*610970, gene) Trafficking protein particle complex 2-like; TRAPPC2LOMIM


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