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> Protein (NX_Q9ULK2)
Protein (NX_Q9ULK2)
Protein
Gene SymbolATXN7L1 to neXtProt (NX_Q9ULK2)
DescriptionAtaxin-7-like protein 1
Chromosome7
Location7q22.3 (105245514 ~ 105517050) to Ensembl
Sequene Features : Isoforms 3, Variants 65, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 65 4
2014-09-19protein level
3 50 4
2014-05-27protein level
3 50 4
2014-02-25protein level
3 50 4
2013-12-09protein level
3 40 4
2013-11-01protein level
3 40 3
2013-09-12protein level
3 40 3
2013-08-17protein level
3 40 3
2013-07-15protein level
3 26 3
2013-06-11protein level
3 26 3
2013-02-12transcript level
3 10 0
2012-12-20transcript level
3 14 0
2012-10-30transcript level
3 20 0
2012-10-07transcript level
3 20 0
2012-08-24transcript level
3 17 0
2012-07-28transcript level
3 16 0
2012-06-08transcript level
3 16 0
2012-05-07transcript level
3 16 0
2012-04-10transcript level
3 16 0
2012-01-13transcript level
3 6 0
2011-12-20transcript level
3 6 0
2011-11-11transcript level
3 6 0
2011-08-23transcript level
3 6 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9ULK2-1
2 30 0 91457.1052
NX_Q9ULK2-2
2 3 0 16199.854
NX_Q9ULK2-3
1 27 0 77825.5802
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-310660,EBI-530034 PHF1  
  .positive regulation of histone H3-K27 methylation
.negative regulation of histone H3-K27 methylation
.negative regulation of gene expression, epigenetic
  + 5 more...
.methylated histone binding
.zinc ion binding
.sequence-specific DNA binding transcription factor activity
.site of double-strand break
.microtubule organizing center
.cytoplasm
  + 2 more...
2 EBI-310660,EBI-10172052 KRTAP10-9  
  .N/A .N/A .keratin filament
3 EBI-310660,EBI-948001 KRT31  
  .epidermis development .structural constituent of cytoskeleton .extracellular exosome
.intermediate filament
.extracellular space
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
bladder33
bone41
bone marrow20
brain17
cervix61
connective tissue6
embryonic tissue18
esophagus49
heart11
intestine43
kidney42
liver14
lung20
lymph45
lymph node11
mammary gland26
muscle18
ovary9
pancreas4
pharynx73
placenta10
prostate15
skin23
spleen37
stomach10
testis48
thymus12
uterus17
Health State
TissuesTPM*
normal23
bladder carcinoma56
breast (mammary gland) tumor42
chondrosarcoma12
colorectal tumor44
esophageal tumor57
gastrointestinal tumor16
germ cell tumor15
glioma46
leukemia10
liver tumor10
lung tumor9
lymphoma27
non-neoplasia10
ovarian tumor13
pancreatic tumor9
primitive neuroectodermal tumor of the CNS15
skin tumor23
soft tissue/muscle tissue tumor23
uterine tumor33
Developmental Stage
TissuesTPM*
adult19
blastocyst32
neonate64
fetus39
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue4.9
adrenal gland3.7
appendix6.2
bone marrow5
cerebral cortex3.8
colon7.3
duodenum9.1
esophagus5.9
gallbladder8.2
heart muscle3.3
kidney13
liver6.1
lung4.4
lymph node9.4
ovary7.5
pancreas1.6
placenta6.1
prostate5.6
salivary gland4.3
skin5.2
small intestine13.9
spleen6.2
stomach5.3
testis24.3
thyroid gland7.9
urinary bladder9.3
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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