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Protein |
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Gene Symbol | SYNRG to neXtProt (NX_Q9UMZ2) |
Description | Synergin gamma |
Chromosome | 17 |
Location | 17q12 (35874900 ~ 35969544) to Ensembl |
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Sequene Features : Isoforms 8, Variants 135, PTMs 20 to neXtProt Sequence Features
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Gene Ontologies |
GO: Biological Process |
GO: Mulecular Function |
GO: Cellular Component |
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.endocytosis .intracellular protein transport |
.N/A |
.AP-1 adaptor complex .Golgi apparatus .cytoplasm |
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Proteomic Evidences |
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Release | | Protein Evidence | | Pr | | Ab | | Isoforms | | Variants | | PTMs |
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2015-01-01 | | protein level | | | | | | | 8 |
| 135 |
| 20 |
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2014-09-19 | | protein level | | | | | | | 8 |
| 106 |
| 20 |
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2014-05-27 | | protein level | | | | | | | 8 |
| 106 |
| 20 |
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2014-02-25 | | protein level | | | | | | | 5 |
| 105 |
| 20 |
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2013-12-09 | | protein level | | | | | | | 5 |
| 80 |
| 20 |
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2013-11-01 | | protein level | | | | | | | 5 |
| 76 |
| 20 |
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2013-09-12 | | protein level | | | | | | | 5 |
| 76 |
| 20 |
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2013-08-17 | | protein level | | | | | | | 5 |
| 76 |
| 20 |
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2013-07-15 | | protein level | | | | | | | 5 |
| 54 |
| 20 |
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2013-06-11 | | protein level | | | | | | | 5 |
| 54 |
| 20 |
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2013-02-12 | | protein level | | | | | | | 5 |
| 29 |
| 87 |
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2012-12-20 | | protein level | | | | | | | 5 |
| 29 |
| 87 |
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2012-10-30 | | protein level | | | | | | | 5 |
| 37 |
| 87 |
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2012-10-07 | | protein level | | | | | | | 5 |
| 37 |
| 18 |
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2012-08-24 | | protein level | | | | | | | 5 |
| 31 |
| 18 |
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2012-07-28 | | protein level | | | | | | | 5 |
| 31 |
| 18 |
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2012-06-08 | | protein level | | | | | | | 5 |
| 35 |
| 18 |
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2012-05-07 | | protein level | | | | | | | 5 |
| 34 |
| 18 |
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2012-04-10 | | protein level | | | | | | | 4 |
| 34 |
| 18 |
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2012-01-13 | | protein level | | | | | | | 4 |
| 14 |
| 18 |
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2011-12-20 | | protein level | | | | | | | 4 |
| 14 |
| 18 |
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2011-11-11 | | protein level | | | | | | | 4 |
| 14 |
| 16 |
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2011-08-23 | | protein level | | | | | | | 4 |
| 14 |
| 14 |
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Protein Isoforms |
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| : Uniquely mapped peptide | | : Gene-specific peptide | | : Shared peptide |
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Interacting Partners |
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No. |
Exp. ref. |
Symbol |
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PE |
Pr |
Ab |
Di |
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GO: Biological Process |
GO: Mulecular Function |
GO: Cellular Component |
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1 |
EBI-7240490,EBI-743771 |
APPBP2 |
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.intracellular transport .metabolic process .intracellular protein transport |
.microtubule motor activity |
.cytoplasmic vesicle membrane .microtubule associated complex .microtubule + 2 more... |
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EST expression level of Protein Coding Gene (ref. NCBI UniGene EST) |
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Body Sites | |
Tissues | TPM* | |
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bladder | 33 | |
blood | 65 | |
bone | 13 | |
bone marrow | 20 | |
brain | 46 | |
cervix | 20 | |
connective tissue | 20 | |
ear | 62 | |
embryonic tissue | 32 | |
eye | 71 | |
heart | 78 | |
intestine | 51 | |
kidney | 99 | |
liver | 24 | |
lung | 116 | |
lymph node | 222 | |
mammary gland | 66 | |
mouth | 90 | |
muscle | 9 | |
nerve | 64 | |
ovary | 49 | |
pancreas | 65 | |
parathyroid | 48 | |
pharynx | 49 | |
pituitary gland | 60 | |
placenta | 10 | |
prostate | 21 | |
skin | 14 | |
spleen | 37 | |
stomach | 20 | |
testis | 55 | |
thymus | 150 | |
thyroid | 64 | |
trachea | 57 | |
uterus | 43 | |
vascular | 19 | |
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Health State | |
Tissues | TPM* | |
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normal | 57 | |
breast (mammary gland) tumor | 42 | |
cervical tumor | 28 | |
chondrosarcoma | 48 | |
colorectal tumor | 35 | |
gastrointestinal tumor | 33 | |
germ cell tumor | 45 | |
glioma | 27 | |
head and neck tumor | 37 | |
kidney tumor | 58 | |
leukemia | 84 | |
liver tumor | 20 | |
lung tumor | 58 | |
lymphoma | 27 | |
non-neoplasia | 62 | |
ovarian tumor | 52 | |
pancreatic tumor | 76 | |
primitive neuroectodermal tumor of the CNS | 15 | |
retinoblastoma | 64 | |
skin tumor | 7 | |
soft tissue/muscle tissue tumor | 23 | |
uterine tumor | 22 | |
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Developmental Stage | |
Tissues | TPM* | |
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adult | 47 | |
blastocyst | 16 | |
fetus | 71 | |
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TPM*: Transcripts per million; transcript expression level measured by expression sequence tags. |
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Expression level of Protein (ref. Human Protein Atlas) |
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RNA-Seq. | |
Tissues | FPKM | |
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adipose tissue | 10.4 | |
adrenal gland | 13.9 | |
appendix | 22.5 | |
bone marrow | 8.5 | |
cerebral cortex | 11.7 | |
colon | 13.4 | |
duodenum | 12.1 | |
esophagus | 14.8 | |
gallbladder | 16.7 | |
heart muscle | 11.3 | |
kidney | 14.3 | |
liver | 6.3 | |
lung | 12.8 | |
lymph node | 31.7 | |
ovary | 12.9 | |
pancreas | 6.8 | |
placenta | 11.7 | |
prostate | 11.6 | |
salivary gland | 9.1 | |
skin | 9.3 | |
small intestine | 13.4 | |
spleen | 23 | |
stomach | 15.6 | |
testis | 30.6 | |
thyroid gland | 16.8 | |
urinary bladder | 18.4 | |
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Cancer | |
Tumor | Number of patients and Staining levels | |
breast cancer | |
carcinoid | |
cervical cancer | |
colorectal cancer | |
endometrial cancer | |
glioma | |
head and neck cancer | |
liver cancer | |
lung cancer | |
lymphoma | |
melanoma | |
ovarian cancer | |
pancreatic cancer | |
prostate cancer | |
renal cancer | |
skin cancer | |
stomach cancer | |
testis cancer | |
thyroid cancer | |
urothelial cancer | |
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RNA-seq colour codes |
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Highly expressed RNAs (FPKM >50) |
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Moderately expressed RNAs (50> FPKM >10) |
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Lower expressed RNAs (10> FPKM >1) |
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The lowest expressed RNAs (FPKM value of 0 or 1) |
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Staining level colour codes |
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Highly expressed protein |
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Moderately expressed protein |
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Lower expressed protein |
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Not Detected |
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Disease |
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No. | Disease Description | Ref. |
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1 | (*607291, gene) Adaptor-related protein complex 1 gamma subunit-binding protein 1; | OMIM |
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