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> Protein (NX_Q9UNK0)
Protein (NX_Q9UNK0)
Protein
Gene SymbolSTX8 to neXtProt (NX_Q9UNK0)
DescriptionSyntaxin-8
Chromosome17
Location17p13.1 (9153788 ~ 9479908) to Ensembl
Sequene Features : Isoforms 1, Variants 31, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of protein localization to plasma membrane
.early endosome to late endosome transport
.endosome to lysosome transport
  + 3 more...
.syntaxin binding
.chloride channel inhibitor activity
.SNAP receptor activity
.recycling endosome
.perinuclear region of cytoplasm
.vesicle
  + 9 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 31 4
2014-09-19protein level
1 27 4
2014-05-27protein level
1 27 4
2014-02-25protein level
1 27 4
2013-12-09protein level
1 22 4
2013-11-01protein level
1 21 2
2013-09-12protein level
1 21 1
2013-08-17protein level
1 21 1
2013-07-15protein level
1 18 0
2013-06-11protein level
1 18 0
2013-02-12protein level
1 8 0
2012-12-20protein level
1 8 0
2012-10-30protein level
1 11 0
2012-10-07protein level
1 11 0
2012-08-24protein level
1 9 0
2012-07-28protein level
1 9 0
2012-06-08protein level
1 10 0
2012-05-07protein level
1 10 0
2012-04-10protein level
1 10 0
2012-01-13protein level
1 6 0
2011-12-20protein level
1 6 0
2011-11-11protein level
1 6 0
2011-08-23protein level
1 6 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9UNK0-1
10 0 0 26889.9311
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-727240,EBI-744942 STX4  
  .positive regulation of protein localization to cell surface
.positive regulation of protein localization to plasma membrane
.regulation of extrinsic apoptotic signaling pathway via death domain receptors
  + 21 more...
.sphingomyelin phosphodiesterase activator activity
.SNAP receptor activity
.SNARE binding
.extracellular exosome
.perinuclear region of cytoplasm
.synapse
  + 19 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland91
blood24
bone69
bone marrow20
brain14
connective tissue40
embryonic tissue18
eye19
heart11
intestine8
kidney28
liver24
lung50
lymph node11
mammary gland19
muscle47
ovary29
pancreas14
parathyroid48
pharynx49
placenta14
prostate15
skin28
stomach10
testis29
uterus8
vascular96
Health State
TissuesTPM*
normal20
adrenal tumor158
breast (mammary gland) tumor10
chondrosarcoma36
colorectal tumor8
germ cell tumor11
glioma18
kidney tumor43
liver tumor31
lung tumor68
non-neoplasia10
ovarian tumor39
pancreatic tumor28
prostate cancer9
retinoblastoma43
skin tumor47
soft tissue/muscle tissue tumor39
uterine tumor11
Developmental Stage
TissuesTPM*
adult24
embryoid body28
blastocyst16
fetus14
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue66.4
adrenal gland82
appendix46.3
bone marrow66.5
cerebral cortex51.6
colon70.7
duodenum47.4
esophagus114.4
gallbladder120.7
heart muscle113.7
kidney63
liver53.4
lung62.8
lymph node101.3
ovary82
pancreas47.7
placenta63.3
prostate60.6
salivary gland76.3
skin90.3
small intestine48.1
spleen47
stomach52
testis116
thyroid gland158.9
urinary bladder136.8
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*604203, gene) Syntaxin 8; STX8OMIM


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