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> Protein (NX_Q9UPQ8)
Protein (NX_Q9UPQ8)
Protein
Gene SymbolDOLK to neXtProt (NX_Q9UPQ8)
DescriptionDolichol kinase
Chromosome9
Location9q34.11 (131707809 ~ 131709898) to Ensembl
Sequene Features : Isoforms 1, Variants 60, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cellular protein metabolic process
.post-translational protein modification
.dolichyl monophosphate biosynthetic process
  + 3 more...
.dolichol kinase activity .integral component of endoplasmic reticulum membrane
.endoplasmic reticulum membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 60 0
2014-09-19protein level
1 48 0
2014-05-27protein level
1 48 0
2014-02-25protein level
1 48 0
2013-12-09protein level
1 40 0
2013-11-01protein level
1 36 0
2013-09-12protein level
1 36 0
2013-08-17protein level
1 36 0
2013-07-15protein level
1 25 0
2013-06-11protein level
1 25 0
2013-02-12protein level
1 17 0
2012-12-20protein level
1 18 0
2012-10-30protein level
1 18 0
2012-10-07protein level
1 18 0
2012-08-24protein level
1 17 0
2012-07-28protein level
1 17 0
2012-06-08protein level
1 24 0
2012-05-07protein level
1 22 0
2012-04-10protein level
1 22 0
2012-01-13protein level
1 14 0
2011-12-20protein level
1 14 0
2011-11-11protein level
1 14 0
2011-08-23protein level
1 14 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9UPQ8-1
18 0 0 59228.725
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-8645574,EBI-529425 EDA  
  .positive regulation of canonical Wnt signaling pathway
.trachea gland development
.hair follicle placode formation
  + 11 more...
.receptor binding .apical part of cell
.intracellular membrane-bounded organelle
.integral component of membrane
  + 7 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
bladder66
blood8
brain26
cervix41
embryonic tissue4
eye23
intestine38
kidney28
liver4
lung11
mammary gland33
mouth15
muscle84
ovary98
pancreas37
placenta38
prostate10
skin9
testis50
tonsil117
uterus8
vascular19
Health State
TissuesTPM*
normal12
adrenal tumor79
breast (mammary gland) tumor53
cervical tumor28
chondrosarcoma12
colorectal tumor53
gastrointestinal tumor16
germ cell tumor37
glioma46
head and neck tumor7
kidney tumor43
leukemia10
liver tumor10
non-neoplasia20
ovarian tumor91
pancreatic tumor66
primitive neuroectodermal tumor of the CNS110
prostate cancer9
retinoblastoma86
skin tumor15
soft tissue/muscle tissue tumor47
Developmental Stage
TissuesTPM*
adult21
embryoid body14
fetus1
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue8.8
adrenal gland8.9
appendix6.1
bone marrow1
cerebral cortex7.3
colon7.8
duodenum6.2
esophagus6.8
gallbladder8.6
heart muscle8.1
kidney9.8
liver5.9
lung9.3
lymph node6.5
ovary6.4
pancreas6.5
placenta9
prostate9
salivary gland8.8
skin8.3
small intestine4.8
spleen6
stomach7.2
testis13.8
thyroid gland8.6
urinary bladder10.1
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Disease
No.Disease DescriptionRef.
1(*610746, gene) Dolichol kinase; DOLKOMIM
2(#610768, phenotype) Congenital disorder of glycosylation, type im; CDG1MOMIM


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