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> Protein (NX_Q9UPT5)
Protein (NX_Q9UPT5)
Protein
Gene SymbolEXOC7 to neXtProt (NX_Q9UPT5)
DescriptionExocyst complex component 7
Chromosome17
Location17q25.1 (74077087 ~ 74117657) to Ensembl
Sequene Features : Isoforms 6, Variants 82, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.membrane organization
.cellular protein metabolic process
.protein transport
  + 2 more...
.N/A .centriolar satellite
.growth cone membrane
.membrane
  + 4 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
6 82 3
2014-09-19protein level
6 56 3
2014-05-27protein level
6 56 3
2014-02-25protein level
6 56 3
2013-12-09protein level
6 43 3
2013-11-01protein level
6 40 1
2013-09-12protein level
6 40 1
2013-08-17protein level
6 40 1
2013-07-15protein level
6 26 1
2013-06-11protein level
6 26 1
2013-02-12protein level
6 11 6
2012-12-20protein level
6 10 6
2012-10-30protein level
6 16 6
2012-10-07protein level
6 16 1
2012-08-24protein level
6 13 1
2012-07-28protein level
6 13 1
2012-06-08protein level
6 17 1
2012-05-07protein level
6 17 1
2012-04-10protein level
6 17 1
2012-01-13protein level
6 9 1
2011-12-20protein level
6 9 1
2011-11-11protein level
6 9 1
2011-08-23protein level
6 9 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9UPT5-1
1 32 0 78011.2351
NX_Q9UPT5-2
0 31 0 74666.4135
NX_Q9UPT5-3
2 33 0 83329.864
NX_Q9UPT5-4
1 11 0 32430.6443
NX_Q9UPT5-5
1 32 0 77254.7056
NX_Q9UPT5-6
1 33 0 80599.5272
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-720048,EBI-10172867 SSC5D  
  .negative regulation of interleukin-8 secretion
.defense response to Gram-positive bacterium
.defense response to Gram-negative bacterium
  + 4 more...
.extracellular matrix binding
.laminin binding
.scavenger receptor activity
.fibronectin binding
.extracellular matrix
.membrane
.cytoplasm
  + 2 more...
2 EBI-720048,EBI-740220 HGS  
  .positive regulation of exosomal secretion
.protein localization to membrane
.membrane organization
  + 13 more...
.metal ion binding
.protein domain specific binding
.extracellular exosome
.intracellular membrane-bounded organelle
.multivesicular body membrane
  + 6 more...
3 EBI-720048,EBI-744203 IFT20  
  .regulation of autophagic vacuole assembly
.regulation of cilium assembly
.protein localization to cilium
  + 13 more...
.N/A .ciliary base
.ciliary tip
.primary cilium
  + 13 more...
4 EBI-720048,EBI-455078 SMARCE1  
  .negative regulation of transcription, DNA-templated
.ATP-dependent chromatin remodeling
.metabolic process
  + 4 more...
.protein N-terminus binding
.ligand-dependent nuclear receptor binding
.N-acetyltransferase activity
  + 4 more...
.nBAF complex
.npBAF complex
.protein complex
  + 6 more...
5 EBI-6251402,EBI-2837511 ARFGEF2  
  .positive regulation of GTPase activity
.intracellular signal transduction
.positive regulation of tumor necrosis factor production
  + 7 more...
.GABA receptor binding
.protein kinase A regulatory subunit binding
.ARF guanyl-nucleotide exchange factor activity
.guanyl-nucleotide exchange factor activity
.recycling endosome
.perinuclear region of cytoplasm
.dendritic spine
  + 11 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
ascites25
bladder200
blood73
bone69
brain127
cervix82
connective tissue60
ear62
embryonic tissue150
eye110
heart55
intestine64
kidney61
larynx42
liver24
lung71
lymph67
lymph node44
mammary gland185
mouth90
muscle28
nerve64
ovary137
pancreas131
pharynx73
pituitary gland60
placenta70
prostate153
salivary gland493
skin123
spleen131
stomach135
testis82
thymus163
thyroid193
trachea57
umbilical cord145
uterus137
vascular58
Health State
TissuesTPM*
normal93
adrenal tumor79
bladder carcinoma341
breast (mammary gland) tumor118
cervical tumor86
chondrosarcoma120
colorectal tumor62
gastrointestinal tumor126
germ cell tumor94
glioma177
head and neck tumor141
kidney tumor58
leukemia137
liver tumor52
lung tumor97
lymphoma69
non-neoplasia41
ovarian tumor131
pancreatic tumor161
primitive neuroectodermal tumor of the CNS94
prostate cancer154
retinoblastoma64
skin tumor151
soft tissue/muscle tissue tumor63
uterine tumor233
Developmental Stage
TissuesTPM*
adult103
embryoid body185
blastocyst179
neonate64
fetus87
infant170
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue36.7
adrenal gland31.8
appendix38.2
bone marrow34.3
cerebral cortex49.1
colon31.1
duodenum35.2
esophagus52
gallbladder43.1
heart muscle39.5
kidney38.2
liver16.9
lung41.4
lymph node36.5
ovary53.5
pancreas23.8
placenta37.1
prostate62.4
salivary gland44.4
skin40.6
small intestine36.5
spleen38
stomach35.7
testis36.2
thyroid gland55.3
urinary bladder54.4
Tissues
TissuesExpression level
adrenal glandHigh
appendixMedium
bone marrowMedium
breastHigh
bronchusHigh
cerebellumHigh
cerebral cortexHigh
cervix, uterineHigh
colonHigh
duodenumHigh
endometrium 1Medium
endometrium 2Medium
epididymisMedium
esophagusMedium
fallopian tubeHigh
gallbladderHigh
heart muscleLow
hippocampusHigh
kidneyMedium
lateral ventricleMedium
liverMedium
lungMedium
lymph nodeMedium
nasopharynxHigh
oral mucosaMedium
ovaryLow
pancreasMedium
parathyroid glandMedium
placentaHigh
prostateMedium
rectumHigh
salivary glandMedium
seminal vesicleMedium
skeletal muscleMedium
skin 1Medium
skin 2Medium
small intestineHigh
smooth muscleMedium
soft tissue 1Medium
soft tissue 2Medium
spleenMedium
stomach 1Medium
stomach 2Medium
testisMedium
thyroid glandMedium
tonsilHigh
urinary bladderHigh
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*608163, gene) Exocyst complex component 7; EXOC7OMIM


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