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> Protein (NX_Q9UPU7)
Protein (NX_Q9UPU7)
Protein
Gene SymbolTBC1D2B to neXtProt (NX_Q9UPU7)
DescriptionTBC1 domain family member 2B
Chromosome15
Location15q24.3 (78276378 ~ 78370066) to Ensembl
Sequene Features : Isoforms 3, Variants 87, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .GTPase activator activity .N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 87 4
2014-09-19protein level
3 78 4
2014-05-27protein level
3 77 4
2014-02-25protein level
3 77 4
2013-12-09protein level
3 54 4
2013-11-01protein level
3 54 4
2013-09-12protein level
3 54 6
2013-08-17protein level
3 54 6
2013-07-15protein level
3 36 6
2013-06-11protein level
3 36 6
2013-02-12protein level
3 25 6
2012-12-20protein level
3 24 6
2012-10-30protein level
3 31 6
2012-10-07protein level
3 31 4
2012-08-24protein level
3 23 4
2012-07-28protein level
3 22 4
2012-06-08protein level
3 22 4
2012-05-07protein level
3 23 4
2012-04-10protein level
3 23 4
2012-01-13protein level
3 10 4
2011-12-20protein level
3 10 4
2011-11-11protein level
3 10 4
2011-08-23protein level
3 10 4
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9UPU7-1
3 38 0 109811.6746
NX_Q9UPU7-2
1 38 0 103851.5162
NX_Q9UPU7-3
0 17 0 36433.4677
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2947180,EBI-712001 GABARAP  
  .membrane fusion
.nucleophagy
.extrinsic apoptotic signaling pathway via death domain receptors
  + 5 more...
.GABA receptor binding
.beta-tubulin binding
.microtubule binding
.perinuclear region of cytoplasm
.cell body
.cytoplasmic vesicle
  + 13 more...
2 EBI-2947180,EBI-720116 GABARAPL2  
  .negative regulation of proteasomal protein catabolic process
.membrane fusion
.nucleophagy
  + 7 more...
.ATPase binding
.GABA receptor binding
.beta-tubulin binding
  + 2 more...
.cytoplasmic vesicle
.extrinsic component of membrane
.cytosol
  + 7 more...
3 EBI-2947180,EBI-2603996 MAP1LC3C  
  .membrane fusion
.nucleophagy
.cellular response to nitrogen starvation
  + 2 more...
.microtubule binding .cytoplasmic vesicle
.organelle membrane
.extrinsic component of membrane
  + 6 more...
4 EBI-2947180,EBI-373144 MAP1LC3B  
  .regulation of mitochondrion degradation
.membrane fusion
.nucleophagy
  + 3 more...
.microtubule binding .cytoplasmic vesicle
.organelle membrane
.extrinsic component of membrane
  + 9 more...
5 EBI-2947180,EBI-746969 GABARAPL1  
  .membrane fusion
.nucleophagy
.mitochondrion degradation
.autophagic vacuole assembly
.GABA receptor binding
.beta-tubulin binding
.Tat protein binding
.microtubule binding
.cell body
.dendrite cytoplasm
.dendrite membrane
  + 10 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland60
ascites25
bladder100
blood40
bone27
bone marrow20
brain37
cervix41
connective tissue80
embryonic tissue37
eye28
intestine43
kidney28
larynx42
lung62
lymph22
lymph node55
mammary gland46
mouth105
muscle65
ovary29
pancreas37
parathyroid48
pharynx24
placenta70
prostate63
skin61
spleen18
stomach83
testis25
thymus301
thyroid21
tonsil58
trachea96
uterus34
vascular19
Health State
TissuesTPM*
normal37
adrenal tumor158
bladder carcinoma56
breast (mammary gland) tumor10
cervical tumor57
chondrosarcoma120
colorectal tumor53
gastrointestinal tumor75
germ cell tumor60
glioma37
head and neck tumor44
kidney tumor43
leukemia52
lung tumor9
lymphoma27
non-neoplasia41
ovarian tumor26
pancreatic tumor66
primitive neuroectodermal tumor of the CNS15
prostate cancer67
skin tumor63
soft tissue/muscle tissue tumor47
uterine tumor22
Developmental Stage
TissuesTPM*
adult41
embryoid body57
blastocyst32
fetus34
infant42
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue22.8
adrenal gland18.2
appendix26.2
bone marrow26.4
cerebral cortex6.3
colon17.7
duodenum15.1
esophagus12.6
gallbladder35.6
heart muscle8.8
kidney9.8
liver14.4
lung36.6
lymph node29.4
ovary47.9
pancreas10.9
placenta27.1
prostate12.4
salivary gland6.8
skin17.3
small intestine19
spleen29.2
stomach16
testis16.4
thyroid gland13.8
urinary bladder28.3
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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