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> Protein (NX_Q9UPV0)
Protein (NX_Q9UPV0)
Protein
Gene SymbolCEP164 to neXtProt (NX_Q9UPV0)
DescriptionCentrosomal protein of 164 kDa
Chromosome11
Location11q23.3 (117185273 ~ 117283984) to Ensembl
Sequene Features : Isoforms 2, Variants 188, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cell division
.cilium assembly
.mitotic nuclear division
  + 4 more...
.N/A .ciliary transition fiber
.cytosol
.centriole
  + 3 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 188 5
2014-09-19protein level
2 149 5
2014-05-27protein level
2 149 5
2014-02-25protein level
2 148 5
2013-12-09protein level
2 110 5
2013-11-01protein level
2 109 5
2013-09-12protein level
2 109 5
2013-08-17protein level
2 109 5
2013-07-15protein level
2 80 3
2013-06-11protein level
2 80 3
2013-02-12protein level
2 49 2
2012-12-20protein level
2 48 2
2012-10-30protein level
2 58 2
2012-10-07protein level
2 58 1
2012-08-24protein level
2 54 1
2012-07-28protein level
2 55 1
2012-06-08protein level
2 5 1
2012-05-07protein level
2 5 1
2012-04-10protein level
2 5 1
2012-01-13protein level
2 5 1
2011-12-20protein level
2 22 1
2011-11-11protein level
2 22 1
2011-08-23protein level
2 22 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9UPV0-1
2 73 0 164213.7793
NX_Q9UPV0-2
1 73 0 163444.3833
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-3937015,EBI-719994 CCDC92  
  .N/A .N/A .centriole
2 EBI-3937015,EBI-1050303 TTBK2  
  .cilium assembly
.peptidyl-serine phosphorylation
.regulation of cell shape
  + 2 more...
.ATP binding
.protein serine/threonine kinase activity
.ciliary basal body
.ciliary transition zone
.cytosol
  + 3 more...
3 EBI-3937015,EBI-2804263 NPHP3  
  .regulation of planar cell polarity pathway involved in neural tube closure
.regulation of Wnt signaling pathway, planar cell polarity pathway
.negative regulation of canonical Wnt signaling pathway
  + 18 more...
.N/A .primary cilium
.cilium
.cytosol
4 EBI-3937015,EBI-739789 DVL3  
  .positive regulation of canonical Wnt signaling pathway
.planar cell polarity pathway involved in neural tube closure
.cochlea morphogenesis
  + 12 more...
.protein heterodimerization activity
.beta-catenin binding
.frizzled binding
  + 2 more...
.cytosol
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bone13
bone marrow102
brain23
connective tissue26
embryonic tissue23
esophagus99
eye47
intestine60
kidney23
larynx42
liver14
lung17
lymph22
lymph node22
mammary gland13
mouth15
muscle65
nerve64
ovary19
pancreas28
pharynx49
prostate15
skin14
stomach20
testis32
thymus12
thyroid42
umbilical cord145
uterus8
vascular19
Health State
TissuesTPM*
normal22
breast (mammary gland) tumor10
chondrosarcoma48
colorectal tumor62
esophageal tumor115
gastrointestinal tumor25
germ cell tumor26
glioma37
head and neck tumor37
kidney tumor14
leukemia21
lung tumor29
lymphoma13
non-neoplasia10
ovarian tumor26
primitive neuroectodermal tumor of the CNS7
retinoblastoma43
skin tumor15
soft tissue/muscle tissue tumor15
uterine tumor11
Developmental Stage
TissuesTPM*
adult23
embryoid body42
blastocyst16
neonate64
fetus25
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue7.7
adrenal gland9.4
appendix14.8
bone marrow7.2
cerebral cortex7
colon7
duodenum5
esophagus10.4
gallbladder12
heart muscle3.8
kidney7.9
liver3.2
lung12.8
lymph node12.6
ovary13.5
pancreas13.6
placenta5.5
prostate8.6
salivary gland5.7
skin15.9
small intestine6.4
spleen15.3
stomach8.9
testis32.7
thyroid gland11.9
urinary bladder10
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(#614845, phenotype) Nephronophthisis 15; NPHP15OMIM
2(*614848, gene) Centrosomal protein, 164-kd; CEP164OMIM


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