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> Protein (NX_Q9Y210)
Protein (NX_Q9Y210)
Protein
Gene SymbolTRPC6 to neXtProt (NX_Q9Y210)
DescriptionShort transient receptor potential channel 6
Chromosome11
Location11q22.1 (101322295 ~ 101743293) to Ensembl
Sequene Features : Isoforms 3, Variants 175, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cellular response to hypoxia
.calcium ion transmembrane transport
.cellular response to hydrogen peroxide
  + 12 more...
.inositol 1,4,5 trisphosphate binding
.store-operated calcium channel activity
.slit diaphragm
.membrane
.integral component of plasma membrane
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 175 3
2014-09-19protein level
3 131 3
2014-05-27protein level
3 131 3
2014-02-25protein level
3 129 3
2013-12-09protein level
3 104 3
2013-11-01protein level
3 101 3
2013-09-12protein level
3 101 3
2013-08-17protein level
3 101 3
2013-07-15protein level
3 71 3
2013-06-11protein level
3 71 3
2013-02-12protein level
3 41 15
2012-12-20protein level
3 41 15
2012-10-30protein level
3 45 15
2012-10-07protein level
3 45 5
2012-08-24protein level
3 20 5
2012-07-28protein level
3 20 5
2012-06-08protein level
3 27 5
2012-05-07protein level
3 27 5
2012-04-10protein level
3 27 5
2012-01-13protein level
3 22 5
2011-12-20protein level
3 22 5
2011-11-11protein level
3 22 5
2011-08-23protein level
3 22 5
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9Y210-1
2 37 5 106257.8341
NX_Q9Y210-2
0 35 5 93126.9755
NX_Q9Y210-3
0 37 5 100041.544
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-929362,EBI-929476 MX1  
  .type I interferon signaling pathway
.defense response to virus
.innate immune response
  + 7 more...
.GTP binding
.GTPase activity
.perinuclear region of cytoplasm
.nuclear membrane
.cytosol
  + 2 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
brain1
eye9
heart33
kidney4
lung17
placenta24
prostate15
trachea19
vascular19
Health State
TissuesTPM*
normal8
lung tumor9
Developmental Stage
TissuesTPM*
adult5
fetus8
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue2.7
appendix1.1
colon1.5
duodenum1.2
esophagus6
gallbladder2.6
kidney1.3
lung13.5
lymph node1.7
placenta14
prostate2.4
skin1.5
small intestine1.3
spleen2.1
stomach1.7
thyroid gland10
urinary bladder2.1
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*603652, gene) Transient receptor potential cation channel, subfamily c, member 6;OMIM
2(#603965, phenotype) Focal segmental glomerulosclerosis 2; FSGS2OMIM


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