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> Protein (NX_Q9Y2I6)
Protein (NX_Q9Y2I6)
Protein
Gene SymbolNINL to neXtProt (NX_Q9Y2I6)
DescriptionNinein-like protein
Chromosome20
Location20p11.21 (25433341 ~ 25566153) to Ensembl
Sequene Features : Isoforms 2, Variants 233, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.organelle organization
.mitotic cell cycle
.G2/M transition of mitotic cell cycle
.calcium ion binding .microtubule
.cytosol
.microtubule organizing center
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 233 0
2014-09-19protein level
2 187 0
2014-05-27protein level
2 186 1
2014-02-25protein level
2 185 1
2013-12-09protein level
2 140 1
2013-11-01protein level
2 135 1
2013-09-12protein level
2 135 1
2013-08-17protein level
2 135 1
2013-07-15protein level
2 93 1
2013-06-11protein level
2 93 1
2013-02-12protein level
2 57 0
2012-12-20protein level
2 52 0
2012-10-30protein level
2 66 0
2012-10-07protein level
2 66 0
2012-08-24protein level
2 60 0
2012-07-28protein level
2 58 0
2012-06-08protein level
2 62 0
2012-05-07protein level
2 62 0
2012-04-10protein level
2 62 0
2012-01-13protein level
2 27 0
2011-12-20protein level
2 27 0
2011-11-11protein level
2 27 0
2011-08-23protein level
2 27 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9Y2I6-1
20 48 0 156247.2922
NX_Q9Y2I6-2
0 48 0 118374.4474
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-719716,EBI-719941 FAM161A  
  .response to stimulus
.cilium assembly
.visual perception
.N/A .ciliary basal body
.photoreceptor connecting cilium
.centrosome
.cytoplasm
2 EBI-719716,EBI-10247802 CCDC146  
  .N/A .N/A .centriole
3 EBI-719716,EBI-8833581 L3MBTL4  
  .chromatin modification
.transcription, DNA-templated
.zinc ion binding
.sequence-specific DNA binding transcription factor activity
.nucleus
4 EBI-719716,EBI-740727 ZNF417  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
5 EBI-719716,EBI-10175300 CCHCR1  
  .cell differentiation
.multicellular organismal development
.protein export from nucleus
.N/A .centriole
.cytoplasm
.nucleus
6 EBI-719716,EBI-399080 KAT5  
  .positive regulation of protein acetylation
.cellular response to estradiol stimulus
.positive regulation of transcription from RNA polymerase II promoter
  + 14 more...
.repressing transcription factor binding
.androgen receptor binding
.metal ion binding
  + 2 more...
.perinuclear region of cytoplasm
.NuA4 histone acetyltransferase complex
.Piccolo NuA4 histone acetyltransferase complex
  + 6 more...
7 EBI-719716,EBI-2514791 HAUS1  
  .cell division
.centrosome organization
.spindle assembly
.mitotic nuclear division
.N/A .HAUS complex
.microtubule
.centrosome
  + 2 more...
8 EBI-719716,EBI-740773 RBM41  
  .N/A .RNA binding
.nucleotide binding
.N/A
9 EBI-719716,EBI-747035 SH2D4A  
  .negative regulation of phosphatase activity .phosphatase binding .cytoplasm
10 EBI-719716,EBI-743428 RCOR3  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.chromatin binding
.DNA binding
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue155
adrenal gland151
bone marrow20
brain16
connective tissue33
embryonic tissue61
esophagus49
eye19
heart44
kidney28
larynx42
liver58
lung50
mouth15
nerve257
ovary9
pancreas65
parathyroid194
pituitary gland60
prostate5
spleen18
stomach20
testis22
thymus37
thyroid21
trachea19
uterus8
Health State
TissuesTPM*
normal21
chondrosarcoma36
esophageal tumor57
gastrointestinal tumor16
germ cell tumor22
head and neck tumor22
liver tumor114
lung tumor9
non-neoplasia20
pancreatic tumor104
primitive neuroectodermal tumor of the CNS31
retinoblastoma64
uterine tumor22
Developmental Stage
TissuesTPM*
adult23
embryoid body57
blastocyst48
fetus34
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue2.5
adrenal gland7.8
appendix2.7
cerebral cortex2.5
colon2
duodenum3.2
esophagus3.5
gallbladder3.6
heart muscle1.9
kidney14.8
liver3.7
lung6
lymph node3.6
ovary14.4
pancreas2
placenta1.7
prostate8.7
salivary gland2.9
skin2.6
small intestine2.3
spleen5.5
stomach4.4
testis7.7
thyroid gland6.4
urinary bladder2.6
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*609580, gene) Ninein-like protein; NINLOMIM


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