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> Protein (NX_Q9Y2J2)
Protein (NX_Q9Y2J2)
Protein
Gene SymbolEPB41L3 to neXtProt (NX_Q9Y2J2)
DescriptionBand 4.1-like protein 3
Chromosome18
Location18p11.31 (5392383 ~ 5630699) to Ensembl
Sequene Features : Isoforms 4, Variants 230, PTMs 22 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.protein localization to plasma membrane
.protein localization to juxtaparanode region of axon
.neuron projection morphogenesis
  + 8 more...
.structural constituent of cytoskeleton .juxtaparanode region of axon
.paranode region of axon
.axolemma
  + 5 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 230 22
2014-09-19protein level
4 174 22
2014-05-27protein level
4 174 26
2014-02-25protein level
3 170 26
2013-12-09protein level
3 158 26
2013-11-01protein level
3 153 19
2013-09-12protein level
3 153 25
2013-08-17protein level
3 153 25
2013-07-15protein level
3 112 23
2013-06-11protein level
3 112 23
2013-02-12protein level
3 44 65
2012-12-20protein level
3 41 65
2012-10-30protein level
3 47 65
2012-10-07protein level
3 47 25
2012-08-24protein level
3 31 25
2012-07-28protein level
3 31 25
2012-06-08protein level
3 33 25
2012-05-07protein level
3 33 25
2012-04-10protein level
3 33 25
2012-01-13protein level
3 15 25
2011-12-20protein level
3 15 25
2011-11-11protein level
3 15 24
2011-08-23protein level
3 15 24
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9Y2J2-1
7 34 5 120602.7975
NX_Q9Y2J2-2
0 34 5 96454.0438
NX_Q9Y2J2-3
0 22 4 69477.6287
NX_Q9Y2J2-4
1 34 4 98399.8928
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10326138,EBI-533224 TCF4  
  .protein-DNA complex assembly
.positive regulation of transcription from RNA polymerase II promoter
.positive regulation of transcription, DNA-templated
  + 3 more...
.E-box binding
.protein heterodimerization activity
.bHLH transcription factor binding
  + 9 more...
.transcription factor complex
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue310
adrenal gland151
brain183
connective tissue73
ear186
embryonic tissue32
esophagus49
eye52
heart11
intestine25
kidney128
larynx42
lung59
lymph node22
mammary gland33
mouth15
muscle9
nerve450
ovary9
pancreas51
parathyroid48
placenta116
prostate5
skin42
stomach10
testis160
thymus25
trachea96
uterus12
vascular38
Health State
TissuesTPM*
normal100
breast (mammary gland) tumor32
chondrosarcoma12
gastrointestinal tumor8
germ cell tumor34
glioma9
head and neck tumor14
kidney tumor232
lung tumor136
lymphoma27
non-neoplasia113
ovarian tumor13
pancreatic tumor28
skin tumor47
soft tissue/muscle tissue tumor15
uterine tumor11
Developmental Stage
TissuesTPM*
adult50
embryoid body42
blastocyst16
fetus57
juvenile125
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue47
adrenal gland58
appendix51.2
bone marrow2.6
cerebral cortex79.3
colon32.5
duodenum87.4
esophagus22.8
gallbladder21.1
heart muscle7.9
kidney67.4
liver4.7
lung25.8
lymph node19.2
ovary21
pancreas6.4
placenta48.3
prostate11.3
salivary gland5.4
skin8.5
small intestine85.5
spleen24
stomach7.9
testis87.7
thyroid gland10
urinary bladder20.5
Tissues
TissuesExpression level
adrenal glandMedium
appendixLow
cerebellumMedium
cerebral cortexMedium
colonMedium
duodenumMedium
epididymisLow
fallopian tubeMedium
gallbladderLow
kidneyMedium
lymph nodeLow
ovaryMedium
pancreasMedium
parathyroid glandMedium
placentaMedium
rectumLow
small intestineMedium
testisMedium
tonsilLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*605331, gene) Erythrocyte membrane protein band 4.1-like 3; EPB41L3OMIM


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