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> Protein (NX_Q9Y2K6)
Protein (NX_Q9Y2K6)
Protein
Gene SymbolUSP20 to neXtProt (NX_Q9Y2K6)
DescriptionUbiquitin carboxyl-terminal hydrolase 20
Chromosome9
Location9q34.11 (132596977 ~ 132644107) to Ensembl
Sequene Features : Isoforms 1, Variants 104, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.protein K48-linked deubiquitination
.protein K63-linked deubiquitination
.regulation of proteasomal protein catabolic process
  + 4 more...
.zinc ion binding
.ubiquitin-specific protease activity
.cysteine-type endopeptidase activity
.G-protein coupled receptor binding
.perinuclear region of cytoplasm
.centrosome
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 104 7
2014-09-19protein level
1 82 7
2014-05-27protein level
1 82 7
2014-02-25protein level
1 82 7
2013-12-09protein level
1 54 7
2013-11-01protein level
1 51 7
2013-09-12protein level
1 51 6
2013-08-17protein level
1 51 6
2013-07-15protein level
1 32 5
2013-06-11protein level
1 32 5
2013-02-12protein level
1 13 10
2012-12-20protein level
1 9 10
2012-10-30protein level
1 21 10
2012-10-07protein level
1 21 10
2012-08-24protein level
1 21 10
2012-07-28protein level
1 19 10
2012-06-08protein level
1 25 10
2012-05-07protein level
1 22 10
2012-04-10protein level
1 22 10
2012-01-13protein level
1 19 10
2011-12-20protein level
1 19 10
2011-11-11protein level
1 19 10
2011-08-23protein level
1 19 10
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9Y2K6-1
41 0 0 101937.9599
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2511991,EBI-742487 SPRY2  
  .positive regulation of protein serine/threonine kinase activity
.positive regulation of ERK1 and ERK2 cascade
.negative regulation of ERK1 and ERK2 cascade
  + 19 more...
.protein serine/threonine kinase activator activity
.protein serine/threonine kinase inhibitor activity
.protein kinase binding
.ruffle membrane
.microtubule cytoskeleton
.plasma membrane
  + 2 more...
2 EBI-2511991,EBI-3905054 ALAS1  
  .small molecule metabolic process
.cellular lipid metabolic process
.mitochondrion organization
  + 4 more...
.pyridoxal phosphate binding
.5-aminolevulinate synthase activity
.mitochondrial matrix
.mitochondrion
.cytoplasm
.nucleoplasm
3 EBI-2511991,EBI-740098 TRIM23  
  .positive regulation of catalytic activity
.protein ubiquitination
.viral process
.small GTPase mediated signal transduction
.identical protein binding
.GDP binding
.ligase activity
  + 5 more...
.extracellular exosome
.lysosomal membrane
.nucleus
.Golgi membrane
4 EBI-2511991,EBI-10178634 MAGEA11  
  .N/A .N/A .cytoplasm
.nucleoplasm
.nucleus
5 EBI-2511991,EBI-724373 BEND5  
  .N/A .N/A .Golgi apparatus
6 EBI-2511991,EBI-8638439 CCDC36  
  .positive regulation of defense response to virus by host .N/A .N/A
7 EBI-2511991,EBI-10181188 BEND7  
  .N/A .N/A .extracellular exosome
8 EBI-2511991,EBI-743099 FATE1  
  .N/A .N/A .integral component of membrane
.endoplasmic reticulum
9 EBI-2511991,EBI-724076 MDFI  
  .trophoblast giant cell differentiation
.embryonic skeletal system morphogenesis
.negative regulation of DNA binding
  + 6 more...
.N/A .cytoplasm
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
ascites25
blood49
bone13
bone marrow102
brain19
cervix41
connective tissue6
embryonic tissue23
esophagus49
eye52
heart44
intestine4
kidney9
liver19
lung20
lymph90
lymph node77
muscle28
nerve128
ovary29
pancreas14
pharynx49
placenta14
prostate26
skin18
spleen56
stomach10
testis50
thymus62
thyroid21
uterus21
Health State
TissuesTPM*
normal28
cervical tumor28
chondrosarcoma24
esophageal tumor57
gastrointestinal tumor16
germ cell tumor18
glioma46
head and neck tumor14
leukemia95
lung tumor29
lymphoma96
non-neoplasia20
ovarian tumor13
pancreatic tumor19
prostate cancer9
skin tumor31
soft tissue/muscle tissue tumor23
uterine tumor11
Developmental Stage
TissuesTPM*
adult26
embryoid body28
blastocyst32
fetus26
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue8.1
adrenal gland14.5
appendix19
bone marrow23.2
cerebral cortex13.7
colon8
duodenum10
esophagus8.6
gallbladder12.7
heart muscle6.7
kidney10.4
liver4.5
lung12
lymph node29.2
ovary13.4
pancreas7.1
placenta9.1
prostate17.8
salivary gland12.4
skin14.2
small intestine10.1
spleen22.9
stomach13.7
testis12.9
thyroid gland16.3
urinary bladder14.1
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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