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> Protein (NX_Q9Y2L9)
Protein (NX_Q9Y2L9)
Protein
Gene SymbolLRCH1 to neXtProt (NX_Q9Y2L9)
DescriptionLeucine-rich repeat and calponin homology domain-containing protein 1
Chromosome13
Location13q14.13 (47127303 ~ 47327175) to Ensembl
Sequene Features : Isoforms 3, Variants 91, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 91 4
2014-09-19protein level
3 75 4
2014-05-27protein level
3 75 4
2014-02-25protein level
3 75 4
2013-12-09protein level
3 52 4
2013-11-01protein level
3 49 4
2013-09-12protein level
3 49 4
2013-08-17protein level
3 49 4
2013-07-15protein level
3 31 4
2013-06-11protein level
3 31 4
2013-02-12protein level
3 14 9
2012-12-20protein level
3 13 9
2012-10-30protein level
2 18 6
2012-10-07protein level
2 18 3
2012-08-24protein level
2 18 3
2012-07-28protein level
2 18 3
2012-06-08protein level
2 18 3
2012-05-07protein level
2 15 3
2012-04-10protein level
2 15 3
2012-01-13protein level
2 6 3
2011-12-20protein level
2 6 3
2011-11-11protein level
2 6 1
2011-08-23protein level
2 6 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9Y2L9-1
0 30 3 80823.8084
NX_Q9Y2L9-2
2 26 3 77176.0267
NX_Q9Y2L9-3
1 29 3 84557.5256
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2797324,EBI-10174653 DOCK8  
  .negative regulation of T cell apoptotic process
.memory T cell proliferation
.dendritic cell migration
  + 3 more...
.guanyl-nucleotide exchange factor activity .cell leading edge
.membrane
.cytosol
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
bladder33
blood8
bone27
brain21
cervix20
connective tissue13
ear62
embryonic tissue9
eye14
intestine38
kidney14
larynx42
liver4
lung17
lymph22
lymph node66
mammary gland39
mouth30
ovary9
pancreas4
placenta42
prostate26
skin33
spleen18
thymus50
uterus30
Health State
TissuesTPM*
normal23
adrenal tumor79
breast (mammary gland) tumor53
cervical tumor28
chondrosarcoma36
colorectal tumor35
germ cell tumor15
glioma9
head and neck tumor22
leukemia10
lung tumor9
lymphoma13
pancreatic tumor9
primitive neuroectodermal tumor of the CNS31
prostate cancer28
retinoblastoma21
skin tumor23
uterine tumor55
Developmental Stage
TissuesTPM*
adult24
embryoid body14
blastocyst16
fetus30
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue12.8
adrenal gland5.3
appendix11.5
bone marrow5.1
cerebral cortex3.1
colon8.5
duodenum7.2
esophagus10.6
gallbladder14.4
heart muscle6.8
kidney12.6
liver7.1
lung11.3
lymph node16
ovary9.8
pancreas3
placenta15.5
prostate10.2
salivary gland7.7
skin12.1
small intestine9.2
spleen13.6
stomach9.4
testis5.5
thyroid gland6.2
urinary bladder13.7
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*610368, gene) Leucine-rich repeats and calponin homology domain-containing 1; LRCH1OMIM


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