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> Protein (NX_Q9Y2T4)
Protein (NX_Q9Y2T4)
Protein
Gene SymbolPPP2R2C to neXtProt (NX_Q9Y2T4)
DescriptionSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform
Chromosome4
Location4p16.1 (6322305 ~ 6565327) to Ensembl
Sequene Features : Isoforms 4, Variants 64, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of protein phosphatase type 2A activity
.signal transduction
.protein phosphatase type 2A regulator activity .protein phosphatase type 2A complex
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 64 0
2014-09-19protein level
4 43 0
2014-05-27protein level
4 43 0
2014-02-25protein level
4 42 0
2013-12-09protein level
4 37 0
2013-11-01transcript level
4 32 0
2013-09-12transcript level
4 32 0
2013-08-17transcript level
4 32 0
2013-07-15transcript level
4 20 0
2013-06-11transcript level
4 20 0
2013-02-12transcript level
4 8 0
2012-12-20transcript level
4 8 0
2012-10-30transcript level
4 10 0
2012-10-07transcript level
4 10 0
2012-08-24transcript level
4 5 0
2012-07-28transcript level
4 5 0
2012-06-08transcript level
4 8 0
2012-05-07transcript level
4 8 0
2012-04-10transcript level
3 8 0
2012-01-13transcript level
3 4 0
2011-12-20transcript level
3 4 0
2011-11-11transcript level
3 4 0
2011-08-23transcript level
3 4 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9Y2T4-1
2 11 4 51482.3719
NX_Q9Y2T4-2
3 11 4 51343.4625
NX_Q9Y2T4-3
1 11 4 49438.4488
NX_Q9Y2T4-4
1 11 4 50604.0257
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1774058,EBI-712311 PPP2CA  
  .positive regulation of protein serine/threonine kinase activity
.protein heterotrimerization
.meiotic cell cycle
  + 25 more...
.metal ion binding
.protein serine/threonine phosphatase activity
.extracellular exosome
.membrane
.microtubule cytoskeleton
  + 7 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
brain272
cervix20
embryonic tissue9
eye14
heart33
kidney33
liver4
lung44
mammary gland19
nerve64
pancreas23
pharynx24
prostate26
skin14
testis59
thymus12
uterus34
Health State
TissuesTPM*
normal94
adrenal tumor79
breast (mammary gland) tumor10
germ cell tumor18
glioma93
head and neck tumor7
kidney tumor29
liver tumor10
non-neoplasia31
uterine tumor66
Developmental Stage
TissuesTPM*
adult127
blastocyst16
fetus23
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adrenal gland6.5
cerebral cortex83.3
esophagus30.3
prostate5.7
skin31.5
small intestine1.2
stomach1.2
testis7.2
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*605997, gene) Protein phosphatase 2, regulatory subunit b, gamma isoform; PPP2R2COMIM


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