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> Protein (NX_Q9Y2V2)
Protein (NX_Q9Y2V2)
Protein
Gene SymbolCARHSP1 to neXtProt (NX_Q9Y2V2)
DescriptionCalcium-regulated heat stable protein 1
Chromosome16
Location16p13.2 (8946799 ~ 8962866) to Ensembl
Sequene Features : Isoforms 1, Variants 26, PTMs 13 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of mRNA stability
.intracellular signal transduction
.regulation of transcription, DNA-templated
.phosphatase binding
.mRNA 3'-UTR binding
.DNA binding
.extracellular exosome
.P granule
.cytosol
.cytoplasmic mRNA processing body
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 26 13
2014-09-19protein level
1 25 13
2014-05-27protein level
1 25 13
2014-02-25protein level
1 25 13
2013-12-09protein level
1 16 13
2013-11-01protein level
1 16 13
2013-09-12protein level
1 16 13
2013-08-17protein level
1 16 13
2013-07-15protein level
1 11 12
2013-06-11protein level
1 11 12
2013-02-12protein level
1 6 11
2012-12-20protein level
1 6 11
2012-10-30protein level
1 9 11
2012-10-07protein level
1 9 11
2012-08-24protein level
1 9 11
2012-07-28protein level
1 9 11
2012-06-08protein level
1 12 11
2012-05-07protein level
1 12 11
2012-04-10protein level
1 12 11
2012-01-13protein level
1 4 11
2011-12-20protein level
1 4 11
2011-11-11protein level
1 4 7
2011-08-23protein level
1 4 7
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9Y2V2-1
6 0 0 15881.9833
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-718719,EBI-10172290 KRTAP10-7  
  .N/A .identical protein binding .keratin filament
2 EBI-718719,EBI-10171774 KRTAP10-8  
  .N/A .N/A .keratin filament
3 EBI-718719,EBI-359224 TRAF1  
  .regulation of extrinsic apoptotic signaling pathway
.positive regulation of NF-kappaB transcription factor activity
.signal transduction
  + 2 more...
.thioesterase binding
.ubiquitin protein ligase binding
.zinc ion binding
.tumor necrosis factor receptor binding
.cytoplasm
4 EBI-718719,EBI-945833 NOTCH2NL  
  .cell differentiation
.multicellular organismal development
.Notch signaling pathway
.calcium ion binding .cytoplasm
.extracellular region
5 EBI-718719,EBI-302345 PNMA1  
  .positive regulation of apoptotic process
.inflammatory response to antigenic stimulus
.N/A .focal adhesion
.cytoplasm
.nucleolus
6 EBI-718719,EBI-2548605 DOCK8  
  .negative regulation of T cell apoptotic process
.memory T cell proliferation
.dendritic cell migration
  + 3 more...
.guanyl-nucleotide exchange factor activity .cell leading edge
.membrane
.cytosol
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue233
adrenal gland30
ascites100
bladder167
blood49
bone97
brain132
cervix185
connective tissue40
embryonic tissue108
eye172
heart145
intestine77
kidney104
liver73
lung86
lymph90
lymph node155
mammary gland39
mouth75
muscle65
nerve64
ovary157
pancreas89
parathyroid242
pituitary gland60
placenta158
prostate31
salivary gland49
skin52
spleen56
stomach41
testis268
thymus87
tonsil117
trachea38
uterus38
vascular135
Health State
TissuesTPM*
normal104
bladder carcinoma56
breast (mammary gland) tumor53
cervical tumor115
chondrosarcoma120
colorectal tumor79
gastrointestinal tumor59
germ cell tumor224
glioma307
head and neck tumor44
kidney tumor43
leukemia137
liver tumor93
lung tumor136
lymphoma55
non-neoplasia62
ovarian tumor131
pancreatic tumor133
primitive neuroectodermal tumor of the CNS62
prostate cancer19
retinoblastoma150
skin tumor63
soft tissue/muscle tissue tumor39
uterine tumor66
Developmental Stage
TissuesTPM*
adult96
embryoid body28
blastocyst211
neonate32
fetus186
infant42
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue37.8
adrenal gland46.8
appendix27.3
bone marrow43.9
cerebral cortex16
colon30.6
duodenum29.3
esophagus59.5
gallbladder34.4
heart muscle17.6
kidney40.4
liver67.4
lung43
lymph node40.3
ovary38.8
pancreas19.1
placenta65.4
prostate15.8
salivary gland22.7
skin14.2
small intestine29.4
spleen29.3
stomach28.4
testis163
thyroid gland14.8
urinary bladder28.1
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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