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> Protein (NX_Q9Y316)
Protein (NX_Q9Y316)
Protein
Gene SymbolMEMO1 to neXtProt (NX_Q9Y316)
DescriptionProtein MEMO1
Chromosome2
Location2p22.3 (32090129 ~ 32236299) to Ensembl
Sequene Features : Isoforms 3, Variants 28, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of microtubule-based process .N/A .cytosol
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 28 2
2014-09-19protein level
3 24 2
2014-05-27protein level
3 24 2
2014-02-25protein level
3 24 2
2013-12-09protein level
3 22 2
2013-11-01protein level
3 22 1
2013-09-12protein level
3 22 1
2013-08-17protein level
2 22 1
2013-07-15protein level
2 14 1
2013-06-11protein level
2 14 1
2013-02-12protein level
2 3 2
2012-12-20protein level
2 3 2
2012-10-30protein level
2 3 2
2012-10-07protein level
2 3 1
2012-08-24protein level
2 0 1
2012-07-28protein level
2 0 1
2012-06-08protein level
2 8 1
2012-05-07protein level
2 11 1
2012-04-10protein level
2 11 1
2012-01-13protein level
2 8 1
2011-12-20protein level
2 8 1
2011-11-11protein level
2 8 1
2011-08-23protein level
2 8 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9Y316-1
0 14 0 33711.3974
NX_Q9Y316-2
0 12 0 31287.3411
NX_Q9Y316-3
2 13 0 34271.7502
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1104564,EBI-624237 TACC1  
  .cell division
.regulation of microtubule-based process
.interkinetic nuclear migration
  + 5 more...
.N/A .intermediate filament cytoskeleton
.microtubule cytoskeleton
.microtubule organizing center
  + 2 more...
2 EBI-1104564,EBI-641062 ERBB2  
  .regulation of ERK1 and ERK2 cascade
.positive regulation of epithelial cell proliferation
.oligodendrocyte differentiation
  + 35 more...
.protein dimerization activity
.protein heterodimerization activity
.ErbB-3 class receptor binding
  + 9 more...
.perinuclear region of cytoplasm
.receptor complex
.cytoplasmic vesicle
  + 7 more...
3 EBI-1104564,EBI-719493 TRIM27  
  .negative regulation of viral release from host cell
.negative regulation of interleukin-2 secretion
.negative regulation of calcium ion import
  + 17 more...
.metal ion binding
.ligase activity
.zinc ion binding
  + 4 more...
.nuclear membrane
.PML body
.membrane
  + 6 more...
4 EBI-1104564,EBI-533224 TCF4  
  .protein-DNA complex assembly
.positive regulation of transcription from RNA polymerase II promoter
.positive regulation of transcription, DNA-templated
  + 3 more...
.E-box binding
.protein heterodimerization activity
.bHLH transcription factor binding
  + 9 more...
.transcription factor complex
.nucleus
5 EBI-1104564,EBI-307352 REL  
  .negative regulation of neuron death
.positive regulation of transcription from RNA polymerase II promoter
.innate immune response
  + 10 more...
.sequence-specific DNA binding transcription factor activity
.chromatin binding
.RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.RNA polymerase II distal enhancer sequence-specific DNA binding
.I-kappaB/NF-kappaB complex
.cytosol
.transcription factor complex
  + 2 more...
6 EBI-1104564,EBI-742327 TRIP6  
  .focal adhesion assembly
.positive regulation of cell migration
.release of cytoplasmic sequestered NF-kappaB
  + 2 more...
.thyroid hormone receptor binding
.poly(A) RNA binding
.kinase binding
  + 2 more...
.focal adhesion
.plasma membrane
.cytoskeleton
  + 2 more...
7 EBI-1104564,EBI-2512147 RBM45  
  .cell differentiation
.nervous system development
.poly(A) RNA binding
.RNA binding
.nucleotide binding
.cytoplasm
.nucleoplasm
.nucleus
8 EBI-1104564,EBI-739832 LNX1  
  .protein homooligomerization
.protein ubiquitination involved in ubiquitin-dependent protein catabolic process
.ligase activity
.zinc ion binding
.ubiquitin-protein transferase activity
.cytoplasm
9 EBI-1104564,EBI-741037 LZTS2  
  .negative regulation of protein localization to nucleus
.negative regulation of canonical Wnt signaling pathway
.spindle midzone assembly
  + 7 more...
.N/A .midbody
.microtubule
.centrosome
.cytoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
ascites100
bladder33
blood16
bone41
brain23
cervix61
connective tissue174
embryonic tissue46
eye47
heart33
intestine17
kidney28
larynx42
liver24
lung23
lymph node33
mammary gland13
muscle28
nerve64
ovary19
pancreas37
pharynx24
pituitary gland60
placenta28
prostate47
skin71
stomach20
testis64
thymus12
trachea19
uterus30
vascular19
Health State
TissuesTPM*
normal30
breast (mammary gland) tumor21
cervical tumor86
chondrosarcoma48
colorectal tumor8
gastrointestinal tumor67
germ cell tumor18
glioma74
head and neck tumor7
kidney tumor14
liver tumor31
lung tumor19
lymphoma27
non-neoplasia72
ovarian tumor13
pancreatic tumor76
primitive neuroectodermal tumor of the CNS31
prostate cancer57
retinoblastoma64
skin tumor79
soft tissue/muscle tissue tumor239
uterine tumor22
Developmental Stage
TissuesTPM*
adult38
embryoid body42
blastocyst16
neonate32
fetus43
infant42
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue7.4
adrenal gland9.4
appendix12.5
bone marrow15.1
cerebral cortex7.2
colon8.1
duodenum8.3
esophagus11.2
gallbladder6
heart muscle11.8
kidney7.9
liver7.4
lung6.3
lymph node12.8
ovary5.3
pancreas3.3
placenta8.6
prostate8.3
salivary gland3.6
skin10.7
small intestine7.7
spleen9.2
stomach6
testis29.3
thyroid gland6.9
urinary bladder11.4
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*611786, gene) Mediator of cell motility 1; MEMO1OMIM


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