Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_Q9Y3C0)
Protein (NX_Q9Y3C0)
Protein
Gene SymbolCCDC53 to neXtProt (NX_Q9Y3C0)
DescriptionWASH complex subunit CCDC53
Chromosome12
Location12q23.2 (102406705 ~ 102455927) to Ensembl
Sequene Features : Isoforms 1, Variants 24, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.protein transport .N/A .WASH complex
.intracellular membrane-bounded organelle
.actin cytoskeleton
.early endosome
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 24 1
2014-09-19protein level
1 19 1
2014-05-27protein level
1 19 1
2014-02-25protein level
1 19 1
2013-12-09protein level
1 11 1
2013-11-01protein level
1 11 1
2013-09-12protein level
1 11 0
2013-08-17protein level
1 11 0
2013-07-15protein level
1 6 0
2013-06-11protein level
1 6 0
2013-02-12protein level
1 1 0
2012-12-20protein level
1 3 0
2012-10-30protein level
1 3 0
2012-10-07protein level
1 3 0
2012-08-24protein level
1 3 0
2012-07-28protein level
1 3 0
2012-06-08protein level
1 5 0
2012-05-07protein level
1 5 0
2012-04-10protein level
1 5 0
2012-01-13protein level
1 9 0
2011-12-20protein level
1 9 0
2011-11-11protein level
1 9 0
2011-08-23protein level
1 9 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9Y3C0-1
8 0 0 21159.5396
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-712969,EBI-727004 SDCBP  
  .positive regulation of extracellular exosome assembly
.positive regulation of exosomal secretion
.ephrin receptor signaling pathway
  + 9 more...
.protein N-terminus binding
.protein heterodimerization activity
.syndecan binding
  + 4 more...
.blood microparticle
.extracellular exosome
.melanosome
  + 12 more...
2 EBI-712969,EBI-715849 NDC80  
  .attachment of mitotic spindle microtubules to kinetochore
.cell division
.attachment of spindle microtubules to kinetochore
  + 7 more...
.identical protein binding
.structural constituent of cytoskeleton
.Ndc80 complex
.membrane
.cytosol
  + 5 more...
3 EBI-712969,EBI-748664 HSBP1  
  .regulation of cellular response to heat
.endodermal cell differentiation
.cellular response to heat
  + 2 more...
.transcription corepressor activity .cytoskeleton
.nucleoplasm
.nucleus
4 EBI-712969,EBI-347978 NUP62  
  .regulation of cellular response to heat
.transmembrane transport
.mRNA transport
  + 34 more...
.thyroid hormone receptor binding
.ubiquitin binding
.SH2 domain binding
  + 3 more...
.Flemming body
.pore complex
.intracellular membrane-bounded organelle
  + 7 more...
5 EBI-712969,EBI-359793 TXLNA  
  .activation of mitophagy in response to mitochondrial depolarization
.B cell activation
.cell proliferation
.exocytosis
.high molecular weight B cell growth factor receptor binding
.cytokine activity
.membrane
.cytoplasm
.extracellular region
6 EBI-712969,EBI-618309 GOLGA2  
  .negative regulation of protein binding
.mitotic cell cycle
.syntaxin binding
.protein kinase binding
.Golgi cisterna membrane
.ER to Golgi transport vesicle
.cis-Golgi network
  + 4 more...
7 EBI-712969,EBI-741421 PCM1  
  .neuronal stem cell maintenance
.positive regulation of intracellular protein transport
.protein localization to centrosome
  + 12 more...
.identical protein binding .protein complex
.ciliary basal body
.centriolar satellite
  + 6 more...
8 EBI-712969,EBI-2558745 MOB1B  
  .protein autophosphorylation
.positive regulation of phosphorylation
.hippo signaling
.metal ion binding
.kinase binding
.kinase activator activity
.extracellular exosome
.cytosol
.cytoplasm
.nucleus
9 EBI-712969,EBI-744203 IFT20  
  .regulation of autophagic vacuole assembly
.regulation of cilium assembly
.protein localization to cilium
  + 13 more...
.N/A .ciliary base
.ciliary tip
.primary cilium
  + 13 more...
10 EBI-712969,EBI-6872807 SYCE1  
  .cell division
.synaptonemal complex assembly
.N/A .central element
11 EBI-712969,EBI-10175300 CCHCR1  
  .cell differentiation
.multicellular organismal development
.protein export from nucleus
.N/A .centriole
.cytoplasm
.nucleus
12 EBI-712969,EBI-740845 PBXIP1  
  .negative regulation of transcription, DNA-templated
.cell differentiation
.multicellular organismal development
.transcription corepressor activity .microtubule
.cytosol
.nucleus
13 EBI-712969,EBI-2514791 HAUS1  
  .cell division
.centrosome organization
.spindle assembly
.mitotic nuclear division
.N/A .HAUS complex
.microtubule
.centrosome
  + 2 more...
14 EBI-712969,EBI-748974 OPTN  
  .Golgi ribbon formation
.defense response to Gram-negative bacterium
.negative regulation of I-kappaB kinase/NF-kappaB signaling
  + 10 more...
.K63-linked polyubiquitin binding
.identical protein binding
.polyubiquitin binding
  + 2 more...
.recycling endosome
.perinuclear region of cytoplasm
.cytoplasmic membrane-bounded vesicle
  + 8 more...
15 EBI-712969,EBI-465804 DTNBP1  
  .membrane organization
.regulation of dopamine receptor signaling pathway
.platelet dense granule organization
  + 11 more...
.N/A .postsynaptic membrane
.dendritic spine
.neuron projection
  + 14 more...
16 EBI-712969,EBI-348259 MCRS1  
  .histone H4-K16 acetylation
.histone H4-K8 acetylation
.histone H4-K5 acetylation
  + 6 more...
.N/A .MLL1 complex
.Ino80 complex
.cell junction
  + 5 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland151
blood24
bone41
bone marrow61
brain24
connective tissue73
embryonic tissue14
eye14
heart89
intestine12
kidney33
liver4
lung53
lymph node89
mammary gland52
mouth30
muscle18
ovary29
pancreas18
parathyroid97
pharynx49
placenta14
prostate26
skin18
stomach10
testis78
thyroid21
uterus30
vascular38
Health State
TissuesTPM*
normal35
breast (mammary gland) tumor32
chondrosarcoma36
colorectal tumor8
gastrointestinal tumor8
germ cell tumor18
glioma65
head and neck tumor14
leukemia21
lymphoma13
non-neoplasia41
ovarian tumor39
pancreatic tumor28
primitive neuroectodermal tumor of the CNS31
prostate cancer19
skin tumor7
soft tissue/muscle tissue tumor87
uterine tumor11
Developmental Stage
TissuesTPM*
adult35
embryoid body14
fetus68
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue25.7
adrenal gland42.8
appendix28.2
bone marrow15.4
cerebral cortex35.9
colon29.4
duodenum21
esophagus34.4
gallbladder37.5
heart muscle37.4
kidney38.7
liver27.5
lung30.8
lymph node38.1
ovary33.9
pancreas12.2
placenta26.6
prostate36.8
salivary gland21
skin24.4
small intestine24.1
spleen25.1
stomach29.3
testis99.7
thyroid gland43.3
urinary bladder44.9
Tissues
TissuesExpression level
adrenal glandLow
breastHigh
cerebral cortexMedium
cervix, uterineLow
colonMedium
endometrium 1Low
salivary glandMedium
skin 1Medium
skin 2Low
smooth muscleHigh
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center