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> Protein (NX_Q9Y3C7)
Protein (NX_Q9Y3C7)
Protein
Gene SymbolMED31 to neXtProt (NX_Q9Y3C7)
DescriptionMediator of RNA polymerase II transcription subunit 31
Chromosome17
Location17p13.1 (6546635 ~ 6554954) to Ensembl
Sequene Features : Isoforms 1, Variants 11, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.limb development
.negative regulation of fibroblast proliferation
.gene expression
  + 2 more...
.RNA polymerase II transcription cofactor activity .mediator complex
.nucleoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 11 1
2014-09-19protein level
1 8 1
2014-05-27protein level
1 8 1
2014-02-25protein level
1 7 1
2013-12-09protein level
1 7 1
2013-11-01protein level
1 6 1
2013-09-12protein level
1 6 0
2013-08-17protein level
1 6 0
2013-07-15protein level
1 3 0
2013-06-11protein level
1 3 0
2013-02-12protein level
1 0 1
2012-12-20protein level
1 0 1
2012-10-30protein level
1 0 1
2012-10-07protein level
1 0 1
2012-08-24protein level
1 0 1
2012-07-28protein level
1 0 1
2012-06-08protein level
1 1 1
2012-05-07protein level
1 1 1
2012-04-10protein level
1 1 1
2012-01-13protein level
1 1 1
2011-12-20protein level
1 1 1
2011-11-11protein level
1 1 1
2011-08-23protein level
1 1 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9Y3C7-1
6 0 0 15794.8792
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-394707,EBI-448202 GADD45G  
  .positive regulation of p38MAPK cascade
.regulation of cell cycle
.positive regulation of JNK cascade
  + 8 more...
.N/A .cytoplasm
.nucleus
2 EBI-394707,EBI-466029 HTT  
  .negative regulation of extrinsic apoptotic signaling pathway
.iron ion homeostasis
.L-glutamate import
  + 38 more...
.diazepam binding
.beta-tubulin binding
.dynein intermediate chain binding
  + 6 more...
.protein complex
.cytoplasmic vesicle membrane
.dendrite
  + 11 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
bladder33
blood24
bone marrow20
brain14
cervix61
connective tissue13
ear62
eye33
heart33
kidney4
larynx42
liver9
lung20
lymph node33
mammary gland6
mouth15
muscle28
nerve64
pancreas4
pharynx98
pituitary gland60
placenta17
prostate47
skin14
testis32
thyroid21
trachea19
umbilical cord72
uterus34
vascular38
Health State
TissuesTPM*
normal22
bladder carcinoma56
breast (mammary gland) tumor10
cervical tumor57
chondrosarcoma24
germ cell tumor7
glioma46
head and neck tumor52
leukemia10
lung tumor9
lymphoma13
non-neoplasia31
pancreatic tumor9
primitive neuroectodermal tumor of the CNS15
prostate cancer77
uterine tumor11
Developmental Stage
TissuesTPM*
adult24
neonate32
fetus28
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue7
adrenal gland16.9
appendix12.3
bone marrow6.5
cerebral cortex13.3
colon9.3
duodenum9.3
esophagus15.2
gallbladder12.8
heart muscle13.3
kidney11.7
liver7.2
lung9.9
lymph node14.8
ovary12.6
pancreas5.3
placenta10.4
prostate11
salivary gland9.1
skin15.1
small intestine6.7
spleen12.4
stomach9.3
testis16.6
thyroid gland14.6
urinary bladder17.6
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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