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> Protein (NX_Q9Y3T9)
Protein (NX_Q9Y3T9)
Protein
Gene SymbolNOC2L to neXtProt (NX_Q9Y3T9)
DescriptionNucleolar complex protein 2 homolog
Chromosome1
Location1p36.33 (879584 ~ 894689) to Ensembl
Sequene Features : Isoforms 1, Variants 103, PTMs 18 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of intrinsic apoptotic signaling pathway
.negative regulation of histone acetylation
.cellular response to UV
  + 6 more...
.repressing transcription factor binding
.poly(A) RNA binding
.histone binding
  + 3 more...
.nucleolus
.nucleoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 103 18
2014-09-19protein level
1 87 18
2014-05-27protein level
1 87 18
2014-02-25protein level
1 87 18
2013-12-09protein level
1 55 18
2013-11-01protein level
1 54 15
2013-09-12protein level
1 54 15
2013-08-17protein level
1 54 15
2013-07-15protein level
1 44 14
2013-06-11protein level
1 44 14
2013-02-12protein level
1 33 24
2012-12-20protein level
1 31 24
2012-10-30protein level
1 37 24
2012-10-07protein level
1 37 24
2012-08-24protein level
1 35 24
2012-07-28protein level
1 35 24
2012-06-08protein level
1 37 24
2012-05-07protein level
1 35 24
2012-04-10protein level
1 35 24
2012-01-13protein level
1 17 24
2011-12-20protein level
1 17 24
2011-11-11protein level
1 17 20
2011-08-23protein level
1 17 20
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9Y3T9-1
31 0 0 84865.9081
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-751547,EBI-708350 ATXN7  
  .positive regulation of transcription from RNA polymerase II promoter
.negative regulation of insulin-like growth factor receptor signaling pathway
.negative regulation of phosphorylation
  + 6 more...
.chromatin binding .nuclear matrix
.microtubule cytoskeleton
.cytoplasm
  + 3 more...
2 EBI-751547,EBI-366083 TP53  
  .positive regulation of intrinsic apoptotic signaling pathway
.positive regulation of reactive oxygen species metabolic process
.negative regulation of reactive oxygen species metabolic process
  + 99 more...
.protein phosphatase 2A binding
.chaperone binding
.protein N-terminus binding
  + 27 more...
.protein complex
.PML body
.nuclear matrix
  + 11 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland60
ascites426
bladder66
blood49
bone139
bone marrow164
brain86
cervix288
connective tissue13
ear62
embryonic tissue140
esophagus49
eye81
heart33
intestine181
kidney113
larynx553
liver102
lung104
lymph248
lymph node33
mammary gland218
mouth151
muscle56
nerve64
ovary167
pancreas84
placenta74
prostate89
salivary gland246
skin260
spleen74
stomach94
testis101
thymus87
thyroid85
trachea19
uterus86
vascular135
Health State
TissuesTPM*
normal63
breast (mammary gland) tumor290
cervical tumor347
chondrosarcoma96
colorectal tumor231
esophageal tumor57
gastrointestinal tumor244
germ cell tumor163
glioma74
head and neck tumor194
kidney tumor159
leukemia116
liver tumor41
lung tumor223
lymphoma193
non-neoplasia10
ovarian tumor131
pancreatic tumor161
primitive neuroectodermal tumor of the CNS236
prostate cancer115
retinoblastoma279
skin tumor398
soft tissue/muscle tissue tumor63
uterine tumor110
Developmental Stage
TissuesTPM*
adult106
embryoid body157
blastocyst244
neonate64
fetus84
infant42
juvenile143
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue14.2
adrenal gland12.6
appendix17.9
bone marrow16
cerebral cortex12.4
colon15.3
duodenum15.2
esophagus19.2
gallbladder12
heart muscle12.6
kidney14.5
liver11.9
lung13.7
lymph node18.9
ovary12.5
pancreas11.8
placenta12.1
prostate18.7
salivary gland13.8
skin27.1
small intestine12.8
spleen17.2
stomach16.2
testis26.4
thyroid gland13.5
urinary bladder13.6
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*610770, gene) Nucleolar complex-associated protein 2, s. cerevisiae, homolog of;OMIM


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