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> Protein (NX_Q9Y4B5)
Protein (NX_Q9Y4B5)
Protein
Gene SymbolMTCL1 to neXtProt (NX_Q9Y4B5)
DescriptionMicrotubule cross-linking factor 1
Chromosome18
Location18p11.22 (8705659 ~ 8832776) to Ensembl
Sequene Features : Isoforms 4, Variants 129, PTMs 37 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of microtubule motor activity
.positive regulation of protein targeting to membrane
.establishment or maintenance of epithelial cell apical/basal polarity
  + 2 more...
.poly(A) RNA binding
.protein homodimerization activity
.microtubule binding
.microtubule bundle
.midbody
.lateral plasma membrane
  + 6 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 129 37
2014-09-19protein level
4 232 37
2014-05-27protein level
4 232 37
2014-02-25protein level
4 129 37
2013-12-09protein level
4 59 37
2013-11-01protein level
4 59 37
2013-09-12protein level
4 59 38
2013-08-17protein level
4 59 38
2013-07-15protein level
4 59 38
2013-06-11protein level
4 59 38
2013-02-12protein level
4 59 119
2012-12-20protein level
4 64 119
2012-10-30protein level
4 72 119
2012-10-07protein level
4 72 37
2012-08-24protein level
4 72 37
2012-07-28protein level
4 70 37
2012-06-08protein level
4 5 37
2012-05-07protein level
4 5 37
2012-04-10protein level
4 5 37
2012-01-13protein level
4 5 37
2011-12-20protein level
4 7 37
2011-11-11protein level
4 7 35
2011-08-23protein level
4 7 35
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9Y4B5-1
21 71 4 209396.8569
NX_Q9Y4B5-2
0 71 4 173203.2389
NX_Q9Y4B5-3
4 70 4 177834.6713
NX_Q9Y4B5-4
7 40 0 108639.4447
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bone55
brain37
connective tissue13
ear62
embryonic tissue37
esophagus49
eye57
heart22
intestine12
kidney14
liver43
lung8
lymph45
lymph node11
muscle9
parathyroid48
pituitary gland60
placenta3
skin23
stomach10
testis11
thymus37
uterus17
Health State
TissuesTPM*
normal23
chondrosarcoma48
colorectal tumor17
esophageal tumor57
gastrointestinal tumor8
germ cell tumor7
glioma18
liver tumor72
lung tumor19
lymphoma41
non-neoplasia10
ovarian tumor13
primitive neuroectodermal tumor of the CNS7
retinoblastoma43
skin tumor7
soft tissue/muscle tissue tumor15
uterine tumor11
Developmental Stage
TissuesTPM*
adult14
embryoid body71
blastocyst16
fetus10
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue1.4
adrenal gland2.5
appendix5
bone marrow1.1
cerebral cortex6.8
colon5.8
duodenum2.4
esophagus5.5
gallbladder20.8
heart muscle3.8
kidney2.9
liver1.1
lung2.8
lymph node2.2
ovary1.8
pancreas1.8
placenta4.8
prostate2.9
skin2.3
small intestine4
spleen1.6
stomach4.8
testis17.5
thyroid gland1.7
urinary bladder18.8
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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