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> Protein (NX_Q9Y4E1)
Protein (NX_Q9Y4E1)
Protein
Gene SymbolFAM21C to neXtProt (NX_Q9Y4E1)
DescriptionWASH complex subunit FAM21C
Chromosome10
Location10q11.22 (46222648 ~ 46288409) to Ensembl
Sequene Features : Isoforms 6, Variants 67, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of barbed-end actin filament capping
.retrograde transport, endosome to plasma membrane
.regulation of substrate adhesion-dependent cell spreading
  + 2 more...
.phosphatidylinositol-3,5-bisphosphate binding
.phosphatidylinositol-4-phosphate binding
.phosphatidylinositol-3,4-bisphosphate binding
  + 4 more...
.WASH complex
.early endosome membrane
.plasma membrane
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
6 67 4
2014-09-19protein level
6 55 4
2014-05-27protein level
6 55 34
2014-02-25protein level
6 55 34
2013-12-09protein level
6 46 34
2013-11-01protein level
6 46 34
2013-09-12protein level
6 46 34
2013-08-17protein level
6 46 34
2013-07-15protein level
6 29 34
2013-06-11protein level
6 29 34
2013-02-12protein level
4 10 168
2012-12-20protein level
4 8 168
2012-10-30protein level
4 11 168
2012-10-07protein level
4 11 42
2012-08-24protein level
4 11 42
2012-07-28protein level
4 11 42
2012-06-08protein level
4 14 42
2012-05-07protein level
4 11 42
2012-04-10protein level
4 11 42
2012-01-13protein level
4 21 42
2011-12-20protein level
4 21 42
2011-11-11protein level
4 21 33
2011-08-23protein level
4 21 33
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9Y4E1-1
0 11 48 144580.1171
NX_Q9Y4E1-2
1 11 47 143561.5711
NX_Q9Y4E1-3
1 11 46 138061.809
NX_Q9Y4E1-4
0 10 49 144823.202
NX_Q9Y4E1-5
1 10 45 136457.7968
NX_Q9Y4E1-6
1 9 46 140058.6586
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites25
bladder33
blood32
bone27
bone marrow61
brain14
cervix82
connective tissue6
ear124
embryonic tissue23
eye23
heart78
intestine30
kidney23
larynx85
liver24
lung26
lymph90
lymph node66
mammary gland59
mouth30
muscle9
ovary19
pancreas42
parathyroid194
pituitary gland60
placenta28
prostate73
salivary gland98
skin33
testis41
thymus62
thyroid128
tonsil176
trachea57
uterus81
Health State
TissuesTPM*
normal51
bladder carcinoma56
breast (mammary gland) tumor32
cervical tumor57
chondrosarcoma12
colorectal tumor26
gastrointestinal tumor16
germ cell tumor45
glioma27
head and neck tumor29
kidney tumor58
leukemia31
liver tumor41
lung tumor48
lymphoma55
non-neoplasia20
ovarian tumor26
pancreatic tumor57
primitive neuroectodermal tumor of the CNS7
prostate cancer86
retinoblastoma86
skin tumor15
soft tissue/muscle tissue tumor15
uterine tumor77
Developmental Stage
TissuesTPM*
adult29
embryoid body42
blastocyst32
neonate64
fetus26
infant42
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue17.2
adrenal gland18.5
appendix20.9
bone marrow27.7
cerebral cortex15.6
colon21.4
duodenum22.7
esophagus19.1
gallbladder20.4
heart muscle21.4
kidney17.2
liver8.7
lung20.8
lymph node27.1
ovary24.9
pancreas6.4
placenta13.7
prostate18.7
salivary gland9.1
skin18.5
small intestine19.4
spleen22.8
stomach15.7
testis15.5
thyroid gland25.3
urinary bladder30.7
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*613631, gene) Family with sequence similarity 21, member c; FAM21COMIM


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