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> Protein (NX_Q9Y5P4)
Protein (NX_Q9Y5P4)
Protein
Gene SymbolCOL4A3BP to neXtProt (NX_Q9Y5P4)
DescriptionCollagen type IV alpha-3-binding protein
Chromosome5
Location5q13.3 (74664311 ~ 74807963) to Ensembl
Sequene Features : Isoforms 3, Variants 54, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.mitochondrion morphogenesis
.lipid homeostasis
.small molecule metabolic process
  + 14 more...
.ceramide binding
.phosphatidylinositol-4-phosphate binding
.ceramide transporter activity
.protein kinase activity
.cytosol
.Golgi apparatus
.endoplasmic reticulum membrane
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 54 3
2014-09-19protein level
3 39 3
2014-05-27protein level
3 39 3
2014-02-25protein level
3 37 3
2013-12-09protein level
3 30 3
2013-11-01protein level
3 30 3
2013-09-12protein level
3 30 5
2013-08-17protein level
3 30 5
2013-07-15protein level
3 22 5
2013-06-11protein level
3 22 5
2013-02-12protein level
3 13 13
2012-12-20protein level
3 13 13
2012-10-30protein level
3 16 13
2012-10-07protein level
3 16 5
2012-08-24protein level
3 11 5
2012-07-28protein level
3 11 5
2012-06-08protein level
3 13 5
2012-05-07protein level
3 13 5
2012-04-10protein level
3 13 5
2012-01-13protein level
3 13 5
2011-12-20protein level
3 13 5
2011-11-11protein level
3 13 5
2011-08-23protein level
3 13 5
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9Y5P4-1
0 31 0 70790.4649
NX_Q9Y5P4-2
1 28 0 67964.1848
NX_Q9Y5P4-3
8 30 0 83655.1861
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-739994,EBI-748380 CSNK1G2  
  .positive regulation of canonical Wnt signaling pathway
.protein autophosphorylation
.small molecule metabolic process
  + 8 more...
.peptide binding
.ATP binding
.protein serine/threonine kinase activity
.magnesium ion binding
.membrane
.cytosol
.nucleus
2 EBI-739994,EBI-712105 ITGB3BP  
  .apoptotic signaling pathway
.cell division
.neurotrophin TRK receptor signaling pathway
  + 10 more...
.protein C-terminus binding
.signal transducer activity
.membrane
.cytosol
.cytoplasm
  + 3 more...
3 EBI-739994,EBI-714543 ARL6IP1  
  .cotranslational protein targeting to membrane .N/A .integral component of membrane
.membrane
.cytosol
.Sec61 translocon complex
4 EBI-739994,EBI-10306917 ACTL8  
  .epithelial cell differentiation .N/A .cytoskeleton
.cytoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
ascites50
bladder33
blood24
bone55
brain39
connective tissue13
embryonic tissue28
eye57
heart78
intestine21
kidney66
larynx85
liver14
lung35
lymph22
lymph node111
mammary gland59
mouth30
muscle37
nerve128
ovary78
pancreas70
parathyroid388
pharynx24
placenta49
prostate42
skin37
spleen93
stomach10
testis50
thymus50
thyroid85
trachea38
uterus34
vascular38
Health State
TissuesTPM*
normal48
bladder carcinoma56
breast (mammary gland) tumor64
chondrosarcoma48
colorectal tumor26
gastrointestinal tumor25
germ cell tumor72
head and neck tumor59
liver tumor31
lymphoma13
non-neoplasia103
ovarian tumor65
pancreatic tumor95
primitive neuroectodermal tumor of the CNS47
prostate cancer28
skin tumor7
soft tissue/muscle tissue tumor15
uterine tumor33
Developmental Stage
TissuesTPM*
adult48
embryoid body57
blastocyst16
neonate32
fetus55
infant85
juvenile71
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue29.5
adrenal gland24.5
appendix17.1
bone marrow19.1
cerebral cortex21.6
colon18.8
duodenum16.7
esophagus24.3
gallbladder23.7
heart muscle14.1
kidney22.6
liver13.4
lung20.7
lymph node19.4
ovary20.3
pancreas7
placenta17.8
prostate20.5
salivary gland8.8
skin14.9
small intestine18.5
spleen20.3
stomach20.6
testis32.6
thyroid gland42.5
urinary bladder23.4
Tissues
TissuesExpression level
adrenal glandHigh
appendixHigh
bone marrowMedium
breastMedium
bronchusHigh
cerebellumMedium
cerebral cortexMedium
cervix, uterineHigh
colonHigh
duodenumHigh
endometrium 1High
epididymisMedium
esophagusHigh
fallopian tubeHigh
gallbladderHigh
hippocampusMedium
kidneyHigh
lateral ventricleHigh
liverLow
lungHigh
lymph nodeMedium
nasopharynxMedium
oral mucosaMedium
ovaryMedium
pancreasHigh
parathyroid glandLow
placentaHigh
prostateHigh
rectumHigh
salivary glandLow
seminal vesicleHigh
skeletal muscleLow
skin 1High
skin 2Medium
small intestineHigh
smooth muscleLow
soft tissue 1Medium
soft tissue 2Medium
spleenHigh
stomach 1High
stomach 2High
testisHigh
thyroid glandHigh
tonsilHigh
urinary bladderHigh
vaginaHigh
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*604677, gene) Collagen, type iv, alpha-3 binding protein; COL4A3BPOMIM


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