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> Protein (NX_Q9Y5Q5)
Protein (NX_Q9Y5Q5)
Protein
Gene SymbolCORIN to neXtProt (NX_Q9Y5Q5)
DescriptionAtrial natriuretic peptide-converting enzyme
Chromosome4
Location4p12 (47596015 ~ 47840123) to Ensembl
Sequene Features : Isoforms 2, Variants 203, PTMs 55 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of renal sodium excretion
.peptide hormone processing
.regulation of blood pressure
  + 2 more...
.serine-type endopeptidase activity .integral component of membrane
.cell surface
.integral component of plasma membrane
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 203 55
2014-09-19protein level
2 160 55
2014-05-27protein level
2 160 55
2014-02-25protein level
2 160 55
2013-12-09protein level
2 133 55
2013-11-01protein level
2 119 55
2013-09-12protein level
2 119 55
2013-08-17protein level
2 119 55
2013-07-15protein level
2 94 55
2013-06-11protein level
2 94 55
2013-02-12protein level
2 41 110
2012-12-20protein level
2 39 110
2012-10-30protein level
2 47 110
2012-10-07protein level
2 47 55
2012-08-24protein level
2 33 55
2012-07-28protein level
2 33 55
2012-06-08protein level
2 46 55
2012-05-07protein level
1 35 55
2012-04-10protein level
1 35 55
2012-01-13protein level
1 21 55
2011-12-20protein level
1 21 55
2011-11-11protein level
1 21 55
2011-08-23protein level
1 21 55
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9Y5Q5-1
3 38 0 116408.2686
NX_Q9Y5Q5-2
1 38 0 113220.669
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bone13
connective tissue60
eye4
heart78
intestine4
muscle18
pancreas4
prostate5
skin9
testis11
trachea38
uterus60
Health State
TissuesTPM*
normal8
chondrosarcoma12
pancreatic tumor9
soft tissue/muscle tissue tumor71
uterine tumor11
Developmental Stage
TissuesTPM*
adult11
fetus1
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
esophagus1.8
gallbladder6.6
heart muscle63.4
lung2.4
prostate2.6
skin8.2
testis2.8
urinary bladder1.6
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Disease
No.Disease DescriptionRef.
1(*605236, gene) Corin, serine peptidase; CORINOMIM
2(#614595, phenotype) Preeclampsia/eclampsia 5; PEE5OMIM


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