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> Protein (NX_Q9Y5Q9)
Protein (NX_Q9Y5Q9)
Protein
Gene SymbolGTF3C3 to neXtProt (NX_Q9Y5Q9)
DescriptionGeneral transcription factor 3C polypeptide 3
Chromosome2
Location2q33.1 (197627756 ~ 197664449) to Ensembl
Sequene Features : Isoforms 2, Variants 74, PTMs 11 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.tRNA transcription from RNA polymerase III promoter
.5S class rRNA transcription from RNA polymerase III type 1 promoter
.gene expression
  + 2 more...
.DNA binding .nucleoplasm
.transcription factor TFIIIC complex
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 74 11
2014-09-19protein level
2 52 11
2014-05-27protein level
2 52 11
2014-02-25protein level
2 52 10
2013-12-09protein level
2 47 10
2013-11-01protein level
2 47 9
2013-09-12protein level
2 47 9
2013-08-17protein level
2 47 9
2013-07-15protein level
2 27 2
2013-06-11protein level
2 27 2
2013-02-12protein level
2 14 2
2012-12-20protein level
2 13 2
2012-10-30protein level
2 13 2
2012-10-07protein level
2 13 1
2012-08-24protein level
2 7 1
2012-07-28protein level
2 7 1
2012-06-08protein level
2 9 1
2012-05-07protein level
2 9 1
2012-04-10protein level
2 9 1
2012-01-13protein level
2 8 1
2011-12-20protein level
2 8 1
2011-11-11protein level
2 8 1
2011-08-23protein level
2 8 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9Y5Q9-1
23 18 0 101207.3535
NX_Q9Y5Q9-2
1 18 0 47227.9254
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1054873,EBI-466029 HTT  
  .negative regulation of extrinsic apoptotic signaling pathway
.iron ion homeostasis
.L-glutamate import
  + 38 more...
.diazepam binding
.beta-tubulin binding
.dynein intermediate chain binding
  + 6 more...
.protein complex
.cytoplasmic vesicle membrane
.dendrite
  + 11 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites125
bladder66
blood32
bone55
bone marrow41
brain63
cervix41
connective tissue33
embryonic tissue65
esophagus49
eye47
intestine51
kidney56
larynx170
liver63
lung17
lymph45
lymph node89
mammary gland112
mouth90
muscle94
nerve128
ovary39
pancreas37
pharynx49
pituitary gland60
placenta60
prostate21
skin52
spleen18
stomach10
testis114
thymus62
trachea135
uterus34
vascular58
Health State
TissuesTPM*
normal58
bladder carcinoma56
breast (mammary gland) tumor107
cervical tumor57
chondrosarcoma72
colorectal tumor53
esophageal tumor57
gastrointestinal tumor50
germ cell tumor72
glioma46
head and neck tumor74
kidney tumor14
leukemia10
liver tumor41
lymphoma27
non-neoplasia20
ovarian tumor39
pancreatic tumor76
primitive neuroectodermal tumor of the CNS47
prostate cancer9
retinoblastoma86
skin tumor47
soft tissue/muscle tissue tumor31
uterine tumor22
Developmental Stage
TissuesTPM*
adult55
embryoid body42
blastocyst81
neonate64
fetus53
infant127
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue12.1
adrenal gland11.7
appendix15.2
bone marrow12.7
cerebral cortex10.8
colon11.7
duodenum11.1
esophagus13.3
gallbladder12.6
heart muscle10.4
kidney11.6
liver5.4
lung13.6
lymph node17
ovary13.7
pancreas7
placenta13
prostate11.3
salivary gland7.3
skin13.2
small intestine13.3
spleen15.4
stomach12
testis17.2
thyroid gland15.7
urinary bladder15
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Disease
No.Disease DescriptionRef.
1(*604888, gene) General transcription factor 3c, polypeptide 3; GTF3C3OMIM


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