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> Protein (NX_Q9Y5X3)
Protein (NX_Q9Y5X3)
Protein
Gene SymbolSNX5 to neXtProt (NX_Q9Y5X3)
DescriptionSorting nexin-5
Chromosome20
Location20p11.23 (17922241 ~ 17949623) to Ensembl
Sequene Features : Isoforms 2, Variants 53, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.retrograde transport, endosome to Golgi
.vesicle organization
.pinocytosis
.intracellular protein transport
.phosphatidylinositol binding
.dynactin binding
.tubular endosome
.macropinocytic cup
.early endosome membrane
  + 6 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 53 5
2014-09-19protein level
1 44 5
2014-05-27protein level
1 44 5
2014-02-25protein level
1 42 5
2013-12-09protein level
1 31 5
2013-11-01protein level
1 30 3
2013-09-12protein level
1 30 3
2013-08-17protein level
1 30 3
2013-07-15protein level
1 16 2
2013-06-11protein level
1 16 2
2013-02-12protein level
1 9 2
2012-12-20protein level
1 9 2
2012-10-30protein level
1 12 2
2012-10-07protein level
1 12 2
2012-08-24protein level
1 10 2
2012-07-28protein level
1 10 2
2012-06-08protein level
1 11 2
2012-05-07protein level
1 11 2
2012-04-10protein level
1 11 2
2012-01-13protein level
1 6 2
2011-12-20protein level
1 6 2
2011-11-11protein level
1 6 2
2011-08-23protein level
1 6 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9Y5X3-1
19 1 1 46787.018
NX_Q9Y5X3-2
6 1 0 13340.7296
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-715760,EBI-743771 APPBP2  
  .intracellular transport
.metabolic process
.intracellular protein transport
.microtubule motor activity .cytoplasmic vesicle membrane
.microtubule associated complex
.microtubule
  + 2 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland242
ascites175
bladder100
blood139
bone153
bone marrow143
brain83
cervix123
connective tissue87
embryonic tissue155
esophagus49
eye114
heart122
intestine176
kidney156
larynx255
liver175
lung116
lymph158
lymph node245
mammary gland119
mouth90
muscle159
nerve193
ovary236
pancreas98
parathyroid534
pharynx147
placenta282
prostate79
salivary gland148
skin166
spleen112
stomach229
testis85
thymus87
thyroid150
tonsil176
trachea96
umbilical cord145
uterus120
vascular135
Health State
TissuesTPM*
normal123
adrenal tumor316
bladder carcinoma113
breast (mammary gland) tumor161
cervical tumor173
chondrosarcoma193
colorectal tumor159
esophageal tumor57
gastrointestinal tumor177
germ cell tumor246
glioma121
head and neck tumor156
kidney tumor14
leukemia84
liver tumor302
lung tumor107
lymphoma193
non-neoplasia103
ovarian tumor288
pancreatic tumor123
primitive neuroectodermal tumor of the CNS78
prostate cancer57
retinoblastoma43
skin tumor159
soft tissue/muscle tissue tumor79
uterine tumor110
Developmental Stage
TissuesTPM*
adult137
embryoid body85
blastocyst195
neonate418
fetus120
infant42
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue49.4
adrenal gland64.1
appendix68.2
bone marrow46.4
cerebral cortex36
colon55.4
duodenum54.1
esophagus31.6
gallbladder44.5
heart muscle31.1
kidney96.8
liver34.2
lung50.7
lymph node94.3
ovary65.7
pancreas17.4
placenta46.6
prostate32.8
salivary gland24.4
skin28.8
small intestine55.9
spleen78.4
stomach44.1
testis33.3
thyroid gland127.9
urinary bladder50.4
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*605937, gene) Sorting nexin 5; SNX5OMIM


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