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> Protein (NX_Q9Y6E0)
Protein (NX_Q9Y6E0)
Protein
Gene SymbolSTK24 to neXtProt (NX_Q9Y6E0)
DescriptionSerine/threonine-protein kinase 24
Chromosome13
Location13q32.2 (99102455 ~ 99230194) to Ensembl
Sequene Features : Isoforms 2, Variants 59, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.execution phase of apoptosis
.regulation of axon regeneration
.protein autophosphorylation
  + 13 more...
.metal ion binding
.ATP binding
.protein serine/threonine kinase activity
.protein kinase activity
.extracellular exosome
.membrane
.cytosol
  + 4 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 59 7
2014-09-19protein level
2 39 7
2014-05-27protein level
2 39 9
2014-02-25protein level
2 38 9
2013-12-09protein level
2 29 9
2013-11-01protein level
2 28 8
2013-09-12protein level
2 28 8
2013-08-17protein level
2 28 8
2013-07-15protein level
2 16 6
2013-06-11protein level
2 16 6
2013-02-12protein level
2 8 15
2012-12-20protein level
2 7 15
2012-10-30protein level
2 9 15
2012-10-07protein level
2 9 9
2012-08-24protein level
2 6 9
2012-07-28protein level
2 6 9
2012-06-08protein level
2 10 9
2012-05-07protein level
2 10 9
2012-04-10protein level
2 10 9
2012-01-13protein level
2 9 9
2011-12-20protein level
2 9 9
2011-11-11protein level
2 9 8
2011-08-23protein level
2 6 8
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9Y6E0-1
2 14 6 49277.1754
NX_Q9Y6E0-2
1 14 6 47883.3567
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-740175,EBI-1046642 STRN  
  .tight junction assembly
.dendrite development
.Wnt signaling pathway
  + 2 more...
.armadillo repeat domain binding
.protein phosphatase 2A binding
.protein complex binding
  + 2 more...
.postsynaptic membrane
.dendritic spine
.neuronal cell body
  + 4 more...
2 EBI-740175,EBI-740195 PDCD10  
  .negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
.Golgi reassembly
.negative regulation of cell migration involved in sprouting angiogenesis
  + 16 more...
.protein N-terminus binding
.protein homodimerization activity
.protein kinase binding
.extracellular exosome
.plasma membrane
.cytosol
  + 3 more...
3 EBI-740175,EBI-1774273 CTTNBP2NL  
  .negative regulation of transmembrane transport
.negative regulation of transporter activity
.protein dephosphorylation
.protein phosphatase 2A binding .actin cytoskeleton
.cytoplasm
4 EBI-740175,EBI-765817 TRAF3IP3  
  .N/A .N/A .integral component of membrane
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland60
ascites251
bladder33
blood57
bone167
brain52
cervix144
connective tissue53
embryonic tissue108
esophagus49
eye81
heart67
intestine112
kidney99
larynx127
liver77
lung95
lymph22
lymph node178
mammary gland66
mouth90
nerve193
ovary39
pancreas89
parathyroid339
pharynx24
pituitary gland121
placenta81
prostate58
skin123
spleen56
stomach125
testis80
thymus25
thyroid42
tonsil58
uterus68
vascular19
Health State
TissuesTPM*
normal78
adrenal tumor158
bladder carcinoma56
breast (mammary gland) tumor64
cervical tumor202
chondrosarcoma169
colorectal tumor124
gastrointestinal tumor160
germ cell tumor83
glioma111
head and neck tumor82
kidney tumor130
leukemia95
liver tumor114
lung tumor48
lymphoma55
non-neoplasia31
ovarian tumor39
pancreatic tumor66
primitive neuroectodermal tumor of the CNS55
prostate cancer77
retinoblastoma43
skin tumor95
soft tissue/muscle tissue tumor31
uterine tumor66
Developmental Stage
TissuesTPM*
adult81
embryoid body114
blastocyst81
fetus62
juvenile107
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue48.5
adrenal gland33.2
appendix59.4
bone marrow41.4
cerebral cortex35.6
colon85
duodenum82.2
esophagus167.5
gallbladder72
heart muscle44.3
kidney55.1
liver20.7
lung46.5
lymph node76.8
ovary43.2
pancreas26.3
placenta64.8
prostate44.1
salivary gland37.9
skin94.2
small intestine100.9
spleen55.1
stomach83.8
testis55.2
thyroid gland70.9
urinary bladder104.9
Tissues
TissuesExpression level
adrenal glandMedium
appendixHigh
bone marrowMedium
breastMedium
bronchusMedium
cerebellumMedium
cerebral cortexMedium
cervix, uterineMedium
colonHigh
duodenumHigh
endometrium 1High
endometrium 2Medium
epididymisMedium
esophagusHigh
fallopian tubeHigh
gallbladderHigh
heart muscleLow
hippocampusMedium
kidneyMedium
lateral ventricleLow
liverMedium
lungMedium
lymph nodeMedium
nasopharynxMedium
oral mucosaMedium
ovaryLow
pancreasMedium
parathyroid glandMedium
placentaHigh
prostateHigh
rectumHigh
salivary glandMedium
seminal vesicleMedium
skeletal muscleLow
skin 1Medium
skin 2Medium
small intestineHigh
smooth muscleLow
soft tissue 1Medium
soft tissue 2Low
spleenMedium
stomach 1High
stomach 2High
testisMedium
thyroid glandMedium
tonsilHigh
urinary bladderHigh
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*604984, gene) Serine/threonine protein kinase 24; STK24OMIM


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