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> Protein (NX_O75460)
Protein (NX_O75460)
Protein
Gene SymbolERN1 to neXtProt (NX_O75460)
DescriptionSerine/threonine-protein kinase/endoribonuclease IRE1
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.peptidyl-serine trans-autophosphorylation
.insulin metabolic process
.positive regulation of endoplasmic reticulum unfolded protein response
.cellular response to glucose stimulus
.intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
.HAC1-type intron splice site recognition and cleavage
.mRNA splicing, via endonucleolytic cleavage and ligation
.protein autophosphorylation
.cellular protein metabolic process
.IRE1-mediated unfolded protein response
.peptidyl-serine autophosphorylation
.cellular response to vascular endothelial growth factor stimulus
.response to endoplasmic reticulum stress
.positive regulation of RNA splicing
.UFP-specific transcription factor mRNA processing involved in endoplasmic reticulum unfolded protein response
.endoplasmic reticulum unfolded protein response
.regulation of macroautophagy
.activation of JUN kinase activity
.cell cycle arrest
.activation of signaling protein activity involved in unfolded protein response
.protein phosphorylation
.mRNA catabolic process
.mRNA cleavage
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.endothelial cell proliferation
.Hsp90 protein binding
.ADP binding
.protein homodimerization activity
.identical protein binding
.Hsp70 protein binding
.enzyme binding
.ATP binding
.protein serine/threonine kinase activity
.endoribonuclease activity
.magnesium ion binding
.IRE1-RACK1-PP2A complex
.IRE1-TRAF2-ASK1 complex
.Ire1 complex
.integral component of endoplasmic reticulum membrane
.endoplasmic reticulum membrane
.endoplasmic reticulum
.mitochondrion
.cytoplasm
.nuclear inner membrane


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