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> Protein (NX_P04637)
Protein (NX_P04637)
Protein
Gene SymbolTP53 to neXtProt (NX_P04637)
DescriptionCellular tumor antigen p53
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of intrinsic apoptotic signaling pathway
.positive regulation of reactive oxygen species metabolic process
.negative regulation of reactive oxygen species metabolic process
.regulation of fibroblast apoptotic process
.positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
.regulation of intrinsic apoptotic signaling pathway by p53 class mediator
.regulation of mitochondrial membrane permeability involved in apoptotic process
.negative regulation of macromitophagy
.positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
.positive regulation of execution phase of apoptosis
.oligodendrocyte apoptotic process
.intrinsic apoptotic signaling pathway
.oxidative stress-induced premature senescence
.replicative senescence
.positive regulation of cell aging
.positive regulation of release of cytochrome c from mitochondria
.intrinsic apoptotic signaling pathway by p53 class mediator
.mitotic cell cycle arrest
.cellular response to ionizing radiation
.cellular response to hypoxia
.positive regulation of cell cycle arrest
.necroptotic process
.positive regulation of thymocyte apoptotic process
.neuron apoptotic process
.protein tetramerization
.negative regulation of helicase activity
.positive regulation of peptidyl-tyrosine phosphorylation
.embryonic organ development
.circadian behavior
.negative regulation of fibroblast proliferation
.regulation of mitochondrial membrane permeability
.response to antibiotic
.positive regulation of transcription from RNA polymerase II promoter
.positive regulation of transcription, DNA-templated
.negative regulation of transcription, DNA-templated
.positive regulation of neuron apoptotic process
.mitochondrial DNA repair
.entrainment of circadian clock by photoperiod
.negative regulation of apoptotic process
.positive regulation of apoptotic process
.regulation of apoptotic process
.intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
.cellular response to glucose starvation
.positive regulation of mitochondrial membrane permeability
.cellular response to drug
.multicellular organism growth
.cellular response to UV
.cellular protein localization
.regulation of tissue remodeling
.T cell differentiation in thymus
.positive regulation of protein oligomerization
.mitotic G1 DNA damage checkpoint
.chromatin assembly
.positive regulation of histone deacetylation
.negative regulation of transforming growth factor beta receptor signaling pathway
.DNA damage response, signal transduction by p53 class mediator
.negative regulation of cell growth
.cell differentiation
.cerebellum development
.viral process
.programmed cell death
.positive regulation of cardiac muscle cell apoptotic process
.gene expression
.response to gamma radiation
.response to X-ray
.response to salt stress
.rRNA transcription
.determination of adult lifespan
.negative regulation of cell proliferation
.cell proliferation
.negative regulation of DNA replication
.protein localization
.blood coagulation
.cell aging
.negative regulation of neuroblast proliferation
.gastrulation
.multicellular organismal development
.Ras protein signal transduction
.Notch signaling pathway
.transforming growth factor beta receptor signaling pathway
.cell cycle arrest
.ER overload response
.DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
.DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
.cellular response to DNA damage stimulus
.apoptotic process
.protein complex assembly
.transcription initiation from RNA polymerase II promoter
.regulation of transcription, DNA-templated
.double-strand break repair
.nucleotide-excision repair
.base-excision repair
.response to ischemia
.T cell lineage commitment
.B cell lineage commitment
.T cell proliferation involved in immune response
.release of cytochrome c from mitochondria
.somitogenesis
.in utero embryonic development
.DNA strand renaturation
.negative regulation of transcription from RNA polymerase II promoter
.protein import into nucleus, translocation
.protein phosphatase 2A binding
.chaperone binding
.protein N-terminus binding
.protein heterodimerization activity
.transcription regulatory region DNA binding
.protein self-association
.identical protein binding
.histone acetyltransferase binding
.histone deacetylase regulator activity
.ubiquitin protein ligase binding
.receptor tyrosine kinase binding
.protein phosphatase binding
.protein kinase binding
.enzyme binding
.zinc ion binding
.transcription factor binding
.ATP binding
.copper ion binding
.sequence-specific DNA binding transcription factor activity
.damaged DNA binding
.chromatin binding
.DNA binding
.p53 binding
.protease binding
.RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.RNA polymerase II transcription factor binding
.RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.core promoter sequence-specific DNA binding
.sequence-specific DNA binding RNA polymerase II transcription factor activity
.RNA polymerase II core promoter sequence-specific DNA binding
.protein complex
.PML body
.nuclear matrix
.cytosol
.endoplasmic reticulum
.mitochondrial matrix
.mitochondrion
.cytoplasm
.nucleolus
.replication fork
.nucleoplasm
.nucleus
.nuclear chromatin
.chromatin


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