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> Protein (NX_P10415)
Protein (NX_P10415)
Gene SymbolBCL2 to neXtProt (NX_P10415)
DescriptionApoptosis regulator Bcl-2
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of intrinsic apoptotic signaling pathway
.negative regulation of intrinsic apoptotic signaling pathway
.negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
.negative regulation of apoptotic signaling pathway
.negative regulation of anoikis
.negative regulation of G1/S transition of mitotic cell cycle
.positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
.intrinsic apoptotic signaling pathway
.extrinsic apoptotic signaling pathway in absence of ligand
.reactive oxygen species metabolic process
.cellular response to hypoxia
.cellular response to organic substance
.intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
.transmembrane transport
.regulation of calcium ion transport
.negative regulation of mitochondrial depolarization
.regulation of mitochondrial membrane potential
.defense response to virus
.neuron apoptotic process
.response to glucocorticoid
.B cell receptor signaling pathway
.homeostasis of number of cells within a tissue
.pigment granule organization
.positive regulation of skeletal muscle fiber development
.oocyte development
.developmental growth
.digestive tract morphogenesis
.thymus development
.spleen development
.focal adhesion assembly
.regulation of mitochondrial membrane permeability
.negative regulation of retinal cell programmed cell death
.positive regulation of melanocyte differentiation
.innate immune response
.regulation of viral genome replication
.ear development
.negative regulation of neuron apoptotic process
.regulation of protein heterodimerization activity
.regulation of protein homodimerization activity
.CD8-positive, alpha-beta T cell lineage commitment
.positive regulation of catalytic activity
.negative regulation of apoptotic process
.T cell homeostasis
.response to hydrogen peroxide
.response to drug
.cellular response to glucose starvation
.B cell proliferation
.positive regulation of multicellular organism growth
.nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
.organ growth
.response to nicotine
.response to cytokine
.negative regulation of osteoblast proliferation
.positive regulation of peptidyl-serine phosphorylation
.T cell differentiation in thymus
.negative regulation of myeloid cell apoptotic process
.negative regulation of cellular pH reduction
.glomerulus development
.endoplasmic reticulum calcium ion homeostasis
.regulation of protein stability
.axon regeneration
.hair follicle morphogenesis
.positive regulation of B cell proliferation
.negative regulation of cell migration
.melanocyte differentiation
.negative regulation of cell growth
.positive regulation of cell growth
.negative regulation of ossification
.regulation of transmembrane transporter activity
.gland morphogenesis
.cochlear nucleus development
.peptidyl-threonine phosphorylation
.peptidyl-serine phosphorylation
.cell growth
.positive regulation of smooth muscle cell migration
.positive regulation of neuron maturation
.mesenchymal cell development
.programmed cell death
.regulation of glycoprotein biosynthetic process
.negative regulation of calcium ion transport into cytosol
.negative regulation of autophagy
.response to gamma radiation
.response to UV-B
.response to iron ion
.post-embryonic development
.response to toxic substance
.response to radiation
.intrinsic apoptotic signaling pathway in response to oxidative stress
.intrinsic apoptotic signaling pathway in response to DNA damage
.extrinsic apoptotic signaling pathway via death domain receptors
.male gonad development
.cell aging
.female pregnancy
.actin filament organization
.cellular response to DNA damage stimulus
.humoral immune response
.apoptotic process
.regulation of nitrogen utilization
.melanin metabolic process
.protein dephosphorylation
.renal system process
.response to ischemia
.B cell lineage commitment
.lymphoid progenitor cell differentiation
.regulation of cell-matrix adhesion
.release of cytochrome c from mitochondria
.B cell homeostasis
.behavioral fear response
.branching involved in ureteric bud morphogenesis
.metanephros development
.ovarian follicle development
.protein polyubiquitination
.BH3 domain binding
.protein heterodimerization activity
.sequence-specific DNA binding
.protein homodimerization activity
.identical protein binding
.ubiquitin protein ligase binding
.channel inhibitor activity
.channel activity
.protease binding
.pore complex
.myelin sheath
.nuclear membrane
.endoplasmic reticulum membrane
.endoplasmic reticulum
.mitochondrial outer membrane

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