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> Protein (NX_P35568)
Protein (NX_P35568)
Protein
Gene SymbolIRS1 to neXtProt (NX_P35568)
DescriptionInsulin receptor substrate 1
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of glucose import in response to insulin stimulus
.JAK-STAT cascade involved in growth hormone signaling pathway
.phosphatidylinositol-mediated signaling
.neurotrophin TRK receptor signaling pathway
.insulin-like growth factor receptor signaling pathway
.negative regulation of insulin secretion
.positive regulation of insulin receptor signaling pathway
.negative regulation of insulin receptor signaling pathway
.positive regulation of glucose import
.positive regulation of glycogen biosynthetic process
.innate immune response
.positive regulation of phosphatidylinositol 3-kinase activity
.protein kinase B signaling
.response to peptide hormone
.glucose homeostasis
.Fc-epsilon receptor signaling pathway
.protein localization to nucleus
.cellular response to insulin stimulus
.response to insulin
.positive regulation of fatty acid beta-oxidation
.mammary gland development
.positive regulation of cell migration
.lipid catabolic process
.phosphatidylinositol 3-kinase signaling
.positive regulation of glucose metabolic process
.regulation of gene expression
.fibroblast growth factor receptor signaling pathway
.insulin receptor signaling pathway
.positive regulation of cell proliferation
.epidermal growth factor receptor signaling pathway
.signal transduction
.positive regulation of mesenchymal cell proliferation
.phosphatidylinositol 3-kinase binding
.SH2 domain binding
.insulin-like growth factor receptor binding
.insulin receptor binding
.protein kinase C binding
.transmembrane receptor protein tyrosine kinase adaptor activity
.signal transducer activity
.intracellular membrane-bounded organelle
.ciliary basal body
.caveola
.insulin receptor complex
.plasma membrane
.cytosol
.cytoplasm
.nucleus


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