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> Protein (NX_P84022)
Protein (NX_P84022)
Protein
Gene SymbolSMAD3 to neXtProt (NX_P84022)
DescriptionMothers against decapentaplegic homolog 3
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of extracellular matrix assembly
.activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
.extrinsic apoptotic signaling pathway
.positive regulation of canonical Wnt signaling pathway
.lens fiber cell differentiation
.negative regulation of wound healing
.SMAD protein signal transduction
.transdifferentiation
.pericardium development
.positive regulation of focal adhesion assembly
.positive regulation of stress fiber assembly
.regulation of binding
.positive regulation of positive chemotaxis
.protein stabilization
.regulation of immune response
.negative regulation of inflammatory response
.regulation of epithelial cell proliferation
.embryonic cranial skeleton morphogenesis
.embryonic foregut morphogenesis
.developmental growth
.paraxial mesoderm morphogenesis
.positive regulation of transcription from RNA polymerase II promoter
.negative regulation of mitotic cell cycle
.positive regulation of transcription, DNA-templated
.negative regulation of osteoblast differentiation
.cell-cell junction organization
.negative regulation of apoptotic process
.positive regulation of transcription factor import into nucleus
.negative regulation of protein catabolic process
.T cell activation
.wound healing
.nodal signaling pathway
.intracellular signal transduction
.positive regulation of catenin import into nucleus
.negative regulation of osteoblast proliferation
.activin receptor signaling pathway
.positive regulation of transforming growth factor beta3 production
.regulation of transforming growth factor beta2 production
.positive regulation of interleukin-1 beta production
.positive regulation of chondrocyte differentiation
.primary miRNA processing
.thyroid gland development
.negative regulation of transforming growth factor beta receptor signaling pathway
.positive regulation of bone mineralization
.positive regulation of cell migration
.negative regulation of cell growth
.signal transduction involved in regulation of gene expression
.evasion or tolerance of host defenses by virus
.regulation of transforming growth factor beta receptor signaling pathway
.regulation of striated muscle tissue development
.positive regulation of epithelial to mesenchymal transition
.positive regulation of alkaline phosphatase activity
.positive regulation of gene expression
.gene expression
.embryonic pattern specification
.endoderm development
.SMAD protein complex assembly
.transforming growth factor beta receptor signaling pathway
.cell cycle arrest
.immune response
.activation of cysteine-type endopeptidase activity involved in apoptotic process
.transport
.transcription initiation from RNA polymerase II promoter
.regulation of transcription from RNA polymerase II promoter
.transcription, DNA-templated
.immune system development
.osteoblast development
.heart looping
.negative regulation of protein phosphorylation
.liver development
.somitogenesis
.mesoderm formation
.in utero embryonic development
.response to hypoxia
.ureteric bud development
.negative regulation of transcription from RNA polymerase II promoter
.R-SMAD binding
.co-SMAD binding
.transcription regulatory region DNA binding
.sequence-specific DNA binding
.bHLH transcription factor binding
.ubiquitin binding
.protein homodimerization activity
.identical protein binding
.enhancer binding
.ubiquitin protein ligase binding
.chromatin DNA binding
.transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
.phosphatase binding
.protein kinase binding
.zinc ion binding
.transcription factor binding
.beta-catenin binding
.transforming growth factor beta receptor binding
.sequence-specific DNA binding transcription factor activity
.double-stranded DNA binding
.RNA polymerase II activating transcription factor binding
.core promoter proximal region sequence-specific DNA binding
.RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity
.RNA polymerase II core promoter proximal region sequence-specific DNA binding
.SMAD2-SMAD3 protein complex
.SMAD protein complex
.receptor complex
.plasma membrane
.cytosol
.cytoplasm
.transcription factor complex
.nucleoplasm
.nuclear inner membrane
.nucleus
.nuclear chromatin


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