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> Protein (NX_Q13485)
Protein (NX_Q13485)
Protein
Gene SymbolSMAD4 to neXtProt (NX_Q13485)
DescriptionMothers against decapentaplegic homolog 4
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.nephrogenic mesenchyme morphogenesis
.metanephric mesenchyme morphogenesis
.response to transforming growth factor beta
.endocardial cell differentiation
.negative regulation of cell death
.SMAD protein signal transduction
.positive regulation of SMAD protein import into nucleus
.palate development
.regulation of hair follicle development
.regulation of binding
.formation of anatomical boundary
.sebaceous gland development
.neuron fate commitment
.developmental growth
.positive regulation of transcription from RNA polymerase II promoter
.positive regulation of transcription, DNA-templated
.negative regulation of transcription, DNA-templated
.negative regulation of protein catabolic process
.endothelial cell activation
.atrioventricular canal development
.intracellular signal transduction
.somatic stem cell maintenance
.regulation of transforming growth factor beta2 production
.somite rostral/caudal axis specification
.positive regulation of BMP signaling pathway
.positive regulation of transforming growth factor beta receptor signaling pathway
.BMP signaling pathway
.negative regulation of cell growth
.regulation of transforming growth factor beta receptor signaling pathway
.neural crest cell differentiation
.positive regulation of pathway-restricted SMAD protein phosphorylation
.positive regulation of epithelial to mesenchymal transition
.gene expression
.negative regulation of cell proliferation
.cell proliferation
.mesoderm development
.endoderm development
.axon guidance
.SMAD protein complex assembly
.transforming growth factor beta receptor signaling pathway
.transcription initiation from RNA polymerase II promoter
.transcription, DNA-templated
.brainstem development
.cardiac septum development
.positive regulation of cell proliferation involved in heart valve morphogenesis
.epithelial to mesenchymal transition involved in endocardial cushion formation
.atrioventricular valve formation
.gastrulation with mouth forming second
.in utero embryonic development
.response to hypoxia
.branching involved in ureteric bud morphogenesis
.negative regulation of transcription from RNA polymerase II promoter
.R-SMAD binding
.I-SMAD binding
.metal ion binding
.transcription regulatory region DNA binding
.protein homodimerization activity
.identical protein binding
.transforming growth factor beta receptor, common-partner cytoplasmic mediator activity
.chromatin binding
.RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.RNA polymerase II transcription factor binding transcription factor activity
.core promoter proximal region sequence-specific DNA binding
.RNA polymerase II core promoter proximal region sequence-specific DNA binding
.SMAD protein complex
.activin responsive factor complex
.cytosol
.centrosome
.cytoplasm
.transcription factor complex
.nucleoplasm
.nucleus
.nuclear chromatin


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