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> Protein (NX_Q14653)
Protein (NX_Q14653)
Protein
Gene SymbolIRF3 to neXtProt (NX_Q14653)
DescriptionInterferon regulatory factor 3
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.programmed necrotic cell death
.macrophage apoptotic process
.cellular response to dsRNA
.positive regulation of type I interferon-mediated signaling pathway
.type I interferon signaling pathway
.interferon-gamma-mediated signaling pathway
.defense response to virus
.positive regulation of cytokine secretion
.negative regulation of defense response to virus by host
.negative regulation of interferon-beta biosynthetic process
.type I interferon biosynthetic process
.innate immune response
.response to exogenous dsRNA
.positive regulation of I-kappaB kinase/NF-kappaB signaling
.MDA-5 signaling pathway
.TRIF-dependent toll-like receptor signaling pathway
.toll-like receptor 4 signaling pathway
.toll-like receptor 3 signaling pathway
.positive regulation of interferon-beta production
.positive regulation of interferon-alpha production
.positive regulation of type I interferon production
.negative regulation of type I interferon production
.lipopolysaccharide-mediated signaling pathway
.cytokine-mediated signaling pathway
.viral process
.cellular response to DNA damage stimulus
.apoptotic process
.transcription from RNA polymerase II promoter
.MyD88-independent toll-like receptor signaling pathway
.toll-like receptor signaling pathway
.negative regulation of transcription from RNA polymerase II promoter
.transcription regulatory region DNA binding
.protein homodimerization activity
.identical protein binding
.transcription cofactor activity
.sequence-specific DNA binding transcription factor activity
.DNA binding
.cytosol
.cytoplasm
.nucleoplasm
.nucleus


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