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> Protein (NX_Q5S007)
Protein (NX_Q5S007)
Protein
Gene SymbolLRRK2 to neXtProt (NX_Q5S007)
DescriptionLeucine-rich repeat serine/threonine-protein kinase 2
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of peroxidase activity
.regulation of synaptic vesicle exocytosis
.regulation of branching morphogenesis of a nerve
.cellular response to dopamine
.negative regulation of protein processing involved in protein targeting to mitochondrion
.negative regulation of protein targeting to mitochondrion
.negative regulation of hydrogen peroxide-induced cell death
.negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation
.negative regulation of late endosome to lysosome transport
.regulation of synaptic vesicle transport
.regulation of neuroblast proliferation
.positive regulation of protein autoubiquitination
.negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
.negative regulation of neuron death
.regulation of neuron death
.regulation of mitochondrial fission
.reactive oxygen species metabolic process
.cellular response to manganese ion
.neuron death
.protein localization to mitochondrion
.regulation of dendritic spine morphogenesis
.positive regulation of dopamine receptor signaling pathway
.regulation of dopamine receptor signaling pathway
.regulation of excitatory postsynaptic membrane potential
.regulation of synaptic transmission, glutamatergic
.regulation of mitochondrial depolarization
.mitochondrion localization
.neuron projection morphogenesis
.intracellular distribution of mitochondria
.protein autophosphorylation
.positive regulation of GTPase activity
.positive regulation of MAP kinase activity
.positive regulation of programmed cell death
.regulation of membrane potential
.regulation of locomotion
.locomotory exploration behavior
.exploration behavior
.regulation of kidney size
.intracellular signal transduction
.cellular protein localization
.cellular response to oxidative stress
.negative regulation of GTPase activity
.positive regulation of proteasomal ubiquitin-dependent protein catabolic process
.positive regulation of protein binding
.negative regulation of protein binding
.positive regulation of protein ubiquitination
.tangential migration from the subventricular zone to the olfactory bulb
.olfactory bulb development
.peptidyl-threonine phosphorylation
.peptidyl-serine phosphorylation
.regulation of neuron maturation
.negative regulation of protein processing
.regulation of protein kinase A signaling
.positive regulation of autophagy
.determination of adult lifespan
.neuromuscular junction development
.small GTPase mediated signal transduction
.mitochondrion organization
.response to oxidative stress
.autophagy
.endocytosis
.protein phosphorylation
.positive regulation of protein phosphorylation
.negative regulation of protein phosphorylation
.activation of MAPK activity
.activation of MAPKK activity
.MAPK cascade
.protein kinase A binding
.ion channel binding
.protein homodimerization activity
.identical protein binding
.peroxidase inhibitor activity
.GTP-dependent protein kinase activity
.clathrin binding
.syntaxin-1 binding
.Rho GTPase binding
.kinase activity
.tubulin binding
.GTP binding
.ATP binding
.GTPase activator activity
.MAP kinase kinase activity
.protein serine/threonine kinase activity
.protein kinase activity
.GTPase activity
.actin binding
.glycoprotein binding
.SNARE binding
.extracellular exosome
.membrane raft
.perikaryon
.terminal bouton
.neuronal cell body
.neuron projection
.dendrite cytoplasm
.cytoplasmic side of mitochondrial outer membrane
.mitochondrial membrane
.cytoplasmic vesicle
.synaptic vesicle membrane
.dendrite
.axon
.cell junction
.inclusion body
.plasma membrane
.cytosol
.trans-Golgi network
.Golgi apparatus
.endoplasmic reticulum
.endosome
.lysosome
.mitochondrial matrix
.mitochondrial inner membrane
.mitochondrial outer membrane
.mitochondrion
.cytoplasm
.extracellular space


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