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> Protein (NX_Q9BXM7)
Protein (NX_Q9BXM7)
Protein
Gene SymbolPINK1 to neXtProt (NX_Q9BXM7)
DescriptionSerine/threonine-protein kinase PINK1, mitochondrial
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of ATP biosynthetic process
.negative regulation of reactive oxygen species metabolic process
.regulation of reactive oxygen species metabolic process
.positive regulation of protein targeting to mitochondrion
.positive regulation of cristae formation
.negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway
.negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway
.regulation of protein targeting to mitochondrion
.negative regulation of oxidative stress-induced neuron death
.negative regulation of oxidative stress-induced cell death
.negative regulation of mitochondrion degradation
.regulation of mitochondrion degradation
.positive regulation of mitochondrial electron transport, NADH to ubiquinone
.negative regulation of autophagic vacuole assembly
.regulation of synaptic vesicle transport
.negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
.activation of mitophagy in response to mitochondrial depolarization
.cellular response to toxic substance
.negative regulation of mitochondrial fission
.positive regulation of release of cytochrome c from mitochondria
.positive regulation of mitochondrial fission
.cellular response to hypoxia
.regulation of proteasomal protein catabolic process
.positive regulation of protein kinase B signaling
.regulation of mitochondrial membrane potential
.positive regulation of ubiquitin-protein transferase activity
.positive regulation of sequence-specific DNA binding transcription factor activity
.protein stabilization
.negative regulation of JNK cascade
.positive regulation of translation
.negative regulation of neuron apoptotic process
.regulation of protein complex assembly
.positive regulation of I-kappaB kinase/NF-kappaB signaling
.TORC2 signaling
.peptidyl-serine autophosphorylation
.intracellular signal transduction
.positive regulation of protein dephosphorylation
.cellular response to oxidative stress
.positive regulation of dopamine secretion
.positive regulation of peptidyl-serine phosphorylation
.positive regulation of synaptic transmission, dopaminergic
.activation of protein kinase B activity
.regulation of protein ubiquitination
.respiratory electron transport chain
.peptidyl-serine phosphorylation
.protein ubiquitination
.phosphorylation
.negative regulation of macroautophagy
.positive regulation of macroautophagy
.positive regulation of peptidase activity
.regulation of mitochondrion organization
.negative regulation of gene expression
.regulation of hydrogen peroxide metabolic process
.mitochondrion organization
.response to oxidative stress
.response to stress
.ubiquitin-dependent protein catabolic process
.protein phosphorylation
.regulation of oxidative phosphorylation
.positive regulation of protein phosphorylation
.mitochondrion degradation
.C3HC4-type RING finger domain binding
.protein kinase B binding
.ubiquitin protein ligase binding
.peptidase activator activity
.kinase activity
.calcium-dependent protein kinase activity
.ATP binding
.protein serine/threonine kinase activity
.protease binding
.magnesium ion binding
.astrocyte projection
.Lewy body
.perinuclear region of cytoplasm
.cell body
.integral component of mitochondrial outer membrane
.axon
.membrane
.cytoskeleton
.cytosol
.mitochondrial intermembrane space
.mitochondrial inner membrane
.mitochondrial outer membrane
.mitochondrion
.cytoplasm
.nucleus
.chromatin


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